2. Gene
  3. Eya1 - EYA transcriptional coactivator and phosphatase 1 Gene

Eya1 - EYA transcriptional coactivator and phosphatase 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: bor

基因 ID: 14048 | 基因类型: protein coding

关于 Eya1

功能概要

Enables RNA binding activity and protein tyrosine Phosphatase activity. Involved in mesodermal cell fate specification; positive regulation of transcription, DNA-templated; and protein sumoylation. Acts upstream of or within several processes, including animal organ development; positive regulation of cell population proliferation; and regulation of signal transduction. Located in cytoplasm and nucleus. Part of protein-DNA complex. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; genitourinary system; and sensory organ. Used to study branchiootorenal syndrome. Human ortholog(s) of this gene implicated in branchiootorenal syndrome and branchiootorenal syndrome 1. Orthologous to human EYA1 (EYA transcriptional coactivator and Phosphatase 1). [provided by Alliance of Genome Resources, Apr 2022]

Eya1 基因产物(7)

mRNA Protein Name
NM_001252192.2 NP_001239121.1 eyes absent homolog 1 isoform 2
NM_001310459.2 NP_001297388.1 eyes absent homolog 1 isoform 3
NM_001402659.1 NP_001389588.1 eyes absent homolog 1 isoform 4
NM_001402660.1 NP_001389589.1 eyes absent homolog 1 isoform 5
NM_001402661.1 NP_001389590.1 eyes absent homolog 1 isoform 6
NM_001402662.1 NP_001389591.1 eyes absent homolog 1 isoform 7
NM_010164.3 NP_034294.2 eyes absent homolog 1 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables RNA binding IDA
IDA: 通过直接分析推断
21936910 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
11734542 MGI
enables protein tyrosine phosphatase activity IDA
IDA: 通过直接分析推断
14628052 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within anatomical structure development IGI
IGI: 通过遗传相互作用推断
16530750 MGI
acts upstream of or within animal organ morphogenesis IMP
IMP: 通过突变表型推断
12070080 MGI
acts upstream of or within aorta morphogenesis IMP
IMP: 通过突变表型推断
21364285 MGI
acts upstream of or within branching involved in ureteric bud morphogenesis IGI
IGI: 通过遗传相互作用推断
12783782 MGI
acts upstream of or within cell fate commitment IMP
IMP: 通过突变表型推断
15817220 MGI
acts upstream of or within cochlea morphogenesis IMP
IMP: 通过突变表型推断
10072433 MGI
acts upstream of or within embryonic skeletal system morphogenesis IMP
IMP: 通过突变表型推断
10471511 MGI
acts upstream of epithelial cell proliferation IMP
IMP: 通过突变表型推断
16916509 MGI
acts upstream of extrinsic apoptotic signaling pathway in absence of ligand IMP
IMP: 通过突变表型推断
15817220 MGI
acts upstream of or within inner ear morphogenesis IGI
IGI: 通过遗传相互作用推断
16916509 MGI
acts upstream of or within inner ear morphogenesis IMP
IMP: 通过突变表型推断
10471511 MGI
involved in mesodermal cell fate specification IDA
IDA: 通过直接分析推断
17785448 MGI
acts upstream of or within metanephros development IMP
IMP: 通过突变表型推断
10072433 MGI
acts upstream of or within middle ear morphogenesis IMP
IMP: 通过突变表型推断
10471511 MGI
acts upstream of or within negative regulation of extrinsic apoptotic signaling pathway in absence of ligand IMP
IMP: 通过突变表型推断
15817220 MGI
acts upstream of or within neuron fate specification IGI
IGI: 通过遗传相互作用推断
22513373 MGI
acts upstream of or within otic vesicle development IGI
IGI: 通过遗传相互作用推断
22513373 MGI
acts upstream of or within otic vesicle morphogenesis IMP
IMP: 通过突变表型推断
16916509 MGI
acts upstream of or within outer ear morphogenesis IMP
IMP: 通过突变表型推断
10471511 MGI
acts upstream of or within outflow tract morphogenesis IMP
IMP: 通过突变表型推断
21364285 MGI
acts upstream of or within pattern specification process IGI
IGI: 通过遗传相互作用推断
16530750 MGI
acts upstream of or within pattern specification process IMP
IMP: 通过突变表型推断
16916509 MGI
acts upstream of or within pharyngeal system development IMP
IMP: 通过突变表型推断
21364285 MGI
involved in positive regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
17785448 MGI
acts upstream of or within positive regulation of epithelial cell proliferation IMP
IMP: 通过突变表型推断
16916509 MGI
acts upstream of or within positive regulation of secondary heart field cardioblast proliferation IGI
IGI: 通过遗传相互作用推断
21364285 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IGI
IGI: 通过遗传相互作用推断
21364285 MGI
acts upstream of or within protein dephosphorylation IDA
IDA: 通过直接分析推断
14628052 MGI
involved in protein sumoylation IDA
IDA: 通过直接分析推断
16990542 MGI
acts upstream of or within regulation of neuron differentiation IGI
IGI: 通过遗传相互作用推断
22513373 MGI
acts upstream of or within regulation of neuron differentiation IMP
IMP: 通过突变表型推断
15496442 MGI
acts upstream of or within semicircular canal morphogenesis IMP
IMP: 通过突变表型推断
10072433 MGI
acts upstream of or within striated muscle tissue development IGI
IGI: 通过遗传相互作用推断
17098221 MGI
acts upstream of or within ureteric bud development IGI
IGI: 通过遗传相互作用推断
16018995 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
16024294 MGI
located in nucleus IDA
IDA: 通过直接分析推断
16024294 MGI
part of protein-DNA complex IDA
IDA: 通过直接分析推断
17785448 MGI
part of protein-containing complex IDA
IDA: 通过直接分析推断
17785448 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

eyes absent homolog 1

eyes absent 1 homolog

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-158059 DS-1-38 Inhibitor 99.60% 否
HY-RS04611 EYA1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22165 Eya1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28687 Eya1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Eya1 NCBI NCBI:2138
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