1. Gene
  2. NEK7 - NIMA related kinase 7 Gene

NEK7 - NIMA related kinase 7 Gene

中文名称:NIMA 相关激酶 7

种属: Homo sapiens

基因 ID: 140609 | 基因类型: protein coding

关于 NEK7

Cytogenetic location: 1q31.3 Genomic coordinates (GRCh38): 1:198,156,998-198,322,420 (from NCBI)

This gene has 8 transcripts (splice variants), 209 orthologues and 8 paralogues. Ubiquitous expression in heart (RPKM 38.5), fat (RPKM 31.8) and 24 other tissues.

功能概要

NIMA 相关激酶与 Aspergillus nidulans ‘never in mitosis A’ 基因的基因产物具有高度氨基酸序列同一性,该基因控制有丝分裂的启动。[OMIM 提供,2002 年 7 月]

NIMA-related kinases share high amino acid sequence identity with the gene product of the Aspergillus nidulans 'never in mitosis A' gene, which controls initiation of mitosis.[supplied by OMIM, Jul 2002]

NEK7 基因产物(1)

mRNA Protein Name
NM_133494.3 NP_598001.1 serine/threonine-protein kinase Nek7

NEK7 蛋白结构

Pkinase

Pkinase: Protein kinase domain (34 - 288)

  • 0
  • 100
  • 200
  • 302 a.a.
蛋白主名 其他名称

serine/threonine-protein kinase Nek7

NIMA (never in mitosis gene a)-related kinase 7

重组 NEK7 蛋白

目录号 产品名 蛋白编号 纯度
HY-P75935 NEK7 Protein, Human (sf9, His-GST) Q8TDX7 (M1-S302) ≥95%

关联疾病

疾病名称 别名
Muckle-Wells Syndrome

MWS

Urticaria-Deafness-Amyloidosis Syndrome

Uda Syndrome

Neutrophilic Urticaria

Urticaria, Deafness And Amyloidosis

Cryopyrin-Associated Periodic Syndrome 2

Caps2

Muckle Wells Syndrome

Urticaria-Deafness-Amyloidosis

Cryopyrin-Associated Periodic Syndromes

Cinca Syndrome

CINCA

Nomid

Cryopyrin-Associated Periodic Syndrome 3

Chronic Neurologic Cutaneous And Articular Syndrome

Multisystem Inflammatory Disease, Neonatal-Onset

Caps3

Chronic Infantile Neurological Cutaneous Articular Syndrome

Infantile-Onset Multisystem Inflammatory Disease

Iomid Syndrome

Neonatal-Onset Multisystem Inflammatory Disease

Nomid Syndrome

Prieur-Griscelli Syndrome

Neonatal Onset Multisystem Inflammatory Disease

Chronic Infantile Neurological, Cutaneous And Articular Syndrome

Iomid

Infantile Onset Multisystem Inflammatory Disease

Prieur Griscelli Syndrome

Chronic Infantile Neurological Cutaneous And Articular Syndrome

Chronic, Infantile, Neurological, Cutaneous, Articular Syndrome

Chronic Infantile Neurologic Cutaneous And Articular Syndrome

Chronic Infantile Neurological, Cutaneous, And Articular Syndrome

Cryopyrin-Associated Periodic Syndromes

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Felis catus NEK7 VGNC VGNC:107901
Rattus norvegicus NEK7 RGD RGD:1311160
Mus musculus NEK7 MGD MGI:1890645
Macaca mulatta NEK7 VGNC VGNC:81484
Bos taurus NEK7 VGNC VGNC:31998
Canis familiaris NEK7 VGNC VGNC:43734
Others NEK7 NCBI