2. Immunology/Inflammation Cell Cycle/DNA Damage
  3. NOD-like Receptor (NLR) NEKs
  4. SLC3037

SLC3037 是一种 NLRP3 抑制剂，阻断 NLRP3 与 NEK7 结合或寡聚化，抑制 MSU 和其他炎性小体激活剂激活的炎性小体。SLC3037 可用于痛风、心血管疾病、代谢综合征或神经退行性疾病的研究。

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SLC3037 Chemical Structure

SLC3037 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

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SLC3037 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

SLC3037 is a NLRP3 inhibitor which blocks NLRP3 from binding to NEK7 or oligomerization, inhibiting inflammasome caused by MSU and other inflammasome activators. SLC3037 can be used for research of gout, cardiovascular diseases, metabolic syndrome or neurodegenerative diseases[1].

IC50 & Target

NLRP3

 

NEK7

 

体外研究
(In Vitro)

SLC3037 (1-10 μM, 5 h) 对脂多糖和 MSU 诱导的 BMDMs IL-1β 有剂量依赖性抑制作用[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

SLC3037 相关抗体:
分子量

529.70

Formula

C29H35N7OS
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

SLC3037 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SLC3037SLC 3037SLC-3037NOD-like Receptor (NLR)NEKsNIMA–related KinasesNIMA (never in mitosis gene a)-related Expressed KinasesNLRP3NEK7inflammasomegoutcardiovascular diseasesmetabolic syndromeneurodegenerative diseaseInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-163358
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