2. Gene
  3. Fer - fer (fms/fps related) protein kinase Gene

Fer - fer (fms/fps related) protein kinase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Fer; Fert; Fert2; C330004K01Rik

基因 ID: 14158 | 基因类型: protein coding

关于 Fer

功能概要

Enables protein kinase activity and protein Phosphatase 1 binding activity. Involved in several processes, including cell surface receptor signaling pathway; cell-cell adhesion mediated by cadherin; and substrate adhesion-dependent cell spreading. Acts upstream of or within several processes, including cell adhesion; chemotaxis; and protein autophosphorylation. Predicted to be located in cytosol and nucleus. Predicted to be extrinsic component of cytoplasmic side of plasma membrane. Predicted to colocalize with several cellular components, including chromatin; cytoskeleton; and lamellipodium. Is expressed in central nervous system and retina. Orthologous to human FER (FER tyrosine kinase). [provided by Alliance of Genome Resources, Apr 2022]

Fer 基因产物(6)

mRNA Protein Name
NM_001037997.4 NP_001033086.2 tyrosine-protein kinase Fer isoform a
NM_001286415.1 NP_001273344.1 tyrosine-protein kinase Fer isoform c
NM_001403359.1 NP_001390288.1 tyrosine-protein kinase Fer isoform d
NM_001403360.1 NP_001390289.1 tyrosine-protein kinase Fer isoform d
NM_001403361.1 NP_001390290.1 tyrosine-protein kinase Fer isoform e
NM_008000.2 NP_032026.2 tyrosine-protein kinase Fer isoform b
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
12200133 MGI
enables protein kinase activity IDA
IDA: 通过直接分析推断
12192036 MGI
enables protein phosphatase 1 binding IPI
IPI: 通过物理相互作用推断
16732323 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in Fc-epsilon receptor signaling pathway IMP
IMP: 通过突变表型推断
12192036 MGI
involved in Kit signaling pathway IMP
IMP: 通过突变表型推断
12192036 MGI
involved in actin cytoskeleton organization IMP
IMP: 通过突变表型推断
16176974 MGI
acts upstream of or within cell adhesion IMP
IMP: 通过突变表型推断
12192036 MGI
involved in cell-cell adhesion mediated by cadherin IMP
IMP: 通过突变表型推断
16176974 MGI
involved in cellular response to reactive oxygen species IMP
IMP: 通过突变表型推断
17606629 MGI
acts upstream of or within chemotaxis IMP
IMP: 通过突变表型推断
12192036 MGI
involved in diapedesis IMP
IMP: 通过突变表型推断
16009680 MGI
involved in extracellular matrix-cell signaling IMP
IMP: 通过突变表型推断
17606629 MGI
involved in insulin receptor signaling pathway IDA
IDA: 通过直接分析推断
11006284 MGI
involved in negative regulation of mast cell activation involved in immune response IMP
IMP: 通过突变表型推断
16731527 MGI
involved in platelet-derived growth factor receptor signaling pathway IDA
IDA: 通过直接分析推断
7623846 MGI
acts upstream of positive effect positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IDA
IDA: 通过直接分析推断
11006284 MGI
acts upstream of or within protein autophosphorylation IDA
IDA: 通过直接分析推断
12192036 MGI
acts upstream of or within protein phosphorylation IDA
IDA: 通过直接分析推断
12192036 MGI
involved in regulation of fibroblast migration IMP
IMP: 通过突变表型推断
17606629 MGI
involved in regulation of protein phosphorylation IMP
IMP: 通过突变表型推断
16732323 MGI
involved in response to lipopolysaccharide IMP
IMP: 通过突变表型推断
16009680 MGI
involved in response to platelet-derived growth factor IDA
IDA: 通过直接分析推断
7623846 MGI
acts upstream of or within signal transduction IDA
IDA: 通过直接分析推断
12192036 MGI
involved in substrate adhesion-dependent cell spreading IMP
IMP: 通过突变表型推断
16176974 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

tyrosine-protein kinase Fer

fer (fms/fps related) protein kinase, testis specific 2

p94-Fer

proto-oncogene c-Fer

proto-oncogene tyrosine-protein kinase Fer

相关产品

Clinical Phase
生物活性分子 (2)
目录号 产品名 作用方式
纯度 Phase
HY-122844 Ifebemtinib Inhibitor 99.86% Phase 2
HY-10338A Foretinib phosphate Inhibitor / Phase 2
Pre-clinical Phase
生物活性分子 (15)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-100579 Ferrostatin-1 Inhibitor 99.96% 否
HY-123919 TL13-112 Inhibitor 98.01% 否
HY-112097 E260 Inhibitor 99.05% 否
HY-148063 DB0614 98.80% 否
HY-122582 TL13-12 Inhibitor 98.06% 否
HY-148061 DB1113 99.22% 否
HY-128576 DS21360717 99.80% 否
HY-136194 TL13-22 Inhibitor 99.71% 否
HY-136195 TL13-110 Inhibitor / 否
HY-156066 Ferrostatin-1 diyne Inhibitor / 否
HY-161731 DS08701581 Inhibitor / 否
HY-RS04862 FER Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS04863 FER1L6 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS16564 Fer Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22996 Fer Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Fer NCBI NCBI:2241
Canis familiaris Fer NCBI NCBI:403754
Felis catus Fer NCBI NCBI:101094235
Macaca fascicularis Fer NCBI NCBI:102143808
Canis lupus familiaris Fer NCBI
Susscrofa domestica Fer NCBI
Rattus norvegicus Fer NCBI NCBI:301737
Macaca mulatta Fer NCBI NCBI:711220
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