2. Gene
  3. FGFBP3 - fibroblast growth factor binding protein 3 Gene

FGFBP3 - fibroblast growth factor binding protein 3 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：成纤维细胞生长因子结合蛋白 3

种属: Homo sapiens

同用名: FGF-BP3; C10orf13

基因 ID: 143282 | 基因类型: protein coding

关于 FGFBP3

This gene has 1 transcript (splice variant), 133 orthologues and 2 paralogues. Biased expression in brain (RPKM 6.6), prostate (RPKM 0.9) and 13 other tissues.

功能概要

启用成纤维细胞生长因子结合活性和肝素结合活性。在成纤维细胞生长因子受体信号通路的正调节和血管通透性的正调节的上游或内部起作用。位于胞外区。 [由基因组资源联盟提供，2022 年 4 月]

Enables Fibroblast Growth Factor binding activity and heparin binding activity. Acts upstream of or within positive regulation of Fibroblast Growth Factor receptor signaling pathway and positive regulation of vascular permeability. Located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022]

FGFBP3 基因产物(1)

mRNA Protein Name
NM_152429.5 NP_689642.3 fibroblast growth factor-binding protein 3 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables fibroblast growth factor binding IPI
IPI: 通过物理相互作用推断
18669637 GOA
enables heparin binding IDA
IDA: 通过直接分析推断
18669637 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within positive regulation of fibroblast growth factor receptor signaling pathway IGI
IGI: 通过遗传相互作用推断
18669637 GOA
acts upstream of or within positive regulation of vascular permeability IDA
IDA: 通过直接分析推断
18669637 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular region IDA
IDA: 通过直接分析推断
18669637 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

FGFBP3 蛋白结构

FGF-BP1

FGF-BP1: FGF binding protein 1 (FGF-BP1) (13 - 258)

  • 0
  • 100
  • 200
  • 258 a.a.
蛋白主名 其他名称

fibroblast growth factor-binding protein 3

FGF-binding protein 3

重组 FGFBP3 蛋白

目录号 产品名 蛋白编号 纯度
HY-P76926 FGFBP3 Protein, Human (sf9, His) Q8TAT2 (R27-G258) ≥95%

关联疾病

疾病名称 别名
Spinal Muscular Atrophy, Type Iv

SMA4

Spinal Muscular Atrophy, Adult Form

Spinal Muscular Atrophy 4

Spinal Muscular Atrophy-4

Adult Spinal Muscular Atrophy

Spinal Muscular Atrophy, Proximal, Adult, Autosomal Recessive

Proximal Spinal Muscular Atrophy Type 4

Sma Type 4

Sma Type Iv

Sma-Iv

Sma Iv

Spinal Muscular Atrophy Adult Form

Spinal Muscular Atrophy Proximal Adult Autosomal Recessive

Spinal Muscular Atrophy Type Iv

Atrophy, Muscular, Spinal, Type Iv

Myelopathic Muscular Atrophy
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04910 FGFBP3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19776 Fgfbp3 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26273 Fgfbp3 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus FGFBP3 MGD MGI:1919764
Rattus norvegicus FGFBP3 RGD RGD:1560326
Canis familiaris FGFBP3 VGNC VGNC:40855
Bos taurus FGFBP3 VGNC VGNC:28984
Macaca mulatta FGFBP3 VGNC VGNC:106049
Others FGFBP3 NCBI
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