2. Gene
  3. Gad1 - glutamate decarboxylase 1 Gene

Gad1 - glutamate decarboxylase 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: EP10; Gad-1

基因 ID: 14415 | 基因类型: protein coding

关于 Gad1

功能概要

The protein encoded by this gene is an enzyme that catalyzes the production of gamma-aminobutyric acid from L-glutamic acid. Alternative splicing of this gene results in two products, the predominant 67 kDa isoform and a smaller 25 kDa isoform. The smaller isoform is not thought to retain catalytic activity. [provided by RefSeq, Aug 2015]

Gad1 基因产物(2)

mRNA Protein Name
NM_001312900.1 NP_001299829.1 glutamate decarboxylase 1 isoform GAD25
NM_008077.5 NP_032103.2 glutamate decarboxylase 1 isoform GAD67
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables glutamate decarboxylase activity IMP
IMP: 通过突变表型推断
9177246 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in gamma-aminobutyric acid biosynthetic process IMP
IMP: 通过突变表型推断
9177246 MGI
acts upstream of or within locomotory exploration behavior IMP
IMP: 通过突变表型推断
24952328 MGI
acts upstream of or within social behavior IMP
IMP: 通过突变表型推断
24952328 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in GABA-ergic synapse IDA
IDA: 通过直接分析推断
21584649 MGI
is active in GABA-ergic synapse IMP
IMP: 通过突变表型推断
21584649 MGI
located in axon IDA
IDA: 通过直接分析推断
12074840 MGI
located in axon terminus IDA
IDA: 通过直接分析推断
11064363 MGI
located in cell cortex IDA
IDA: 通过直接分析推断
11064363 MGI
located in cytoplasm IDA
IDA: 通过直接分析推断
15347806 MGI
located in inhibitory synapse IDA
IDA: 通过直接分析推断
24613359 MGI
located in neuron projection terminus IDA
IDA: 通过直接分析推断
12074840 MGI
is active in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
29960053 MGI
is active in presynapse IDA
IDA: 通过直接分析推断
21584649 MGI
is active in presynapse IMP
IMP: 通过突变表型推断
21584649 MGI
located in presynaptic active zone IDA
IDA: 通过直接分析推断
12074840 MGI
located in synapse IDA
IDA: 通过直接分析推断
15479642 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

glutamate decarboxylase 1

67 kDa glutamic acid decarboxylase

glutamic acid decarboxylase 1

相关产品

Approval
生物活性分子 (4)
目录号 产品名 作用方式
纯度 是否罕见病
HY-B0161A Duloxetine hydrochloride Inhibitor 99.97% 是
HY-B0161 Duloxetine Inhibitor 99.92% 是
HY-118901 Opipramol Antagonist 99.91% 否
HY-B0161AR Duloxetine hydrochloride (Standard) Inhibitor / 否
Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-122487 Troriluzole Modulator 99.71% Phase 3
Pre-clinical Phase
生物活性分子 (9)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-118901A Opipramol dihydrochloride Antagonist / 否
HY-122487A Troriluzole hydrochloride Modulator / 否
HY-B0161AS Duloxetine-d3 hydrochloride Inhibitor / 否
HY-B0161AS1 Duloxetine-d7 hydrochloride Inhibitor / 否
HY-RS05227 GAD1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-B0161S Duloxetine-d7 Inhibitor / 否
HY-B0161S3 Duloxetine-d5 oxalate Inhibitor / 否
HY-RS17368 Gad1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23822 Gad1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Gad1 NCBI NCBI:2571
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