2. Gene
  3. B4galt1 - UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 Gene

B4galt1 - UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: GalT; Ggtb; Ggtb2; b4Gal-T1; B-1,4-GalT; B-1,4-GalT1; beta4Gal-T1; beta-1,4-GalT; beta-1,4-GalT1

基因 ID: 14595 | 基因类型: protein coding

关于 B4galt1

功能概要

This gene encodes two distinct enzyme isoforms, a long membrane-bound form and a short soluble form. These alternate isoforms are thought to be produced through alternative nested transcription initiation and different in-frame start codon usage. These Enzymes catalyze the transfer of galactose to acceptor sugars, such as N-acetylglucosamine and glucose. The long form of this enzyme is localized to the trans-Golgi membrane and is involved in glycoconjugate biosynthesis. The short form functions in lactose biosynthesis though formation of a heterodimer with alpha-lactalbumin. [provided by RefSeq, Nov 2012]

B4galt1 基因产物(4)

mRNA Protein Name
NM_001378519.2 NP_001365448.1 beta-1,4-galactosyltransferase 1 isoform 2
NM_022305.6 NP_071641.1 beta-1,4-galactosyltransferase 1 isoform 1
NM_001378519.2 NP_001365448.1 beta-1,4-galactosyltransferase 1 isoform 2
NM_022305.6 NP_071641.1 beta-1,4-galactosyltransferase 1 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity IDA
IDA: 通过直接分析推断
9813328 MGI
enables beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity IMP
IMP: 通过突变表型推断
9013935 MGI
enables galactosyltransferase activity IDA
IDA: 通过直接分析推断
7641815 MGI
enables lactose synthase activity IMP
IMP: 通过突变表型推断
9155011 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
8089187 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within acute inflammatory response IMP
IMP: 通过突变表型推断
12714507 MGI
acts upstream of or within angiogenesis involved in wound healing IMP
IMP: 通过突变表型推断
15039218 MGI
acts upstream of or within binding of sperm to zona pellucida IMP
IMP: 通过突变表型推断
9374408 MGI
acts upstream of or within binding of sperm to zona pellucida IPI
IPI: 通过物理相互作用推断
8089187 MGI
acts upstream of or within cell adhesion IGI
IGI: 通过遗传相互作用推断
12714507 MGI
acts upstream of cell population proliferation IMP
IMP: 通过突变表型推断
9155011 MGI
acts upstream of or within development of secondary sexual characteristics IMP
IMP: 通过突变表型推断
11900463 MGI
acts upstream of or within epithelial cell development IMP
IMP: 通过突变表型推断
9155011 MGI
acts upstream of epithelial cell proliferation IMP
IMP: 通过突变表型推断
9155011 MGI
acts upstream of or within extracellular matrix organization IMP
IMP: 通过突变表型推断
11900463 MGI
acts upstream of or within galactose metabolic process IDA
IDA: 通过直接分析推断
9813328 MGI
acts upstream of or within glycoprotein biosynthetic process IMP
IMP: 通过突变表型推断
10381349 MGI
acts upstream of or within lactose biosynthetic process IMP
IMP: 通过突变表型推断
9155011 MGI
involved in lactose biosynthetic process IMP
IMP: 通过突变表型推断
9155011 MGI
acts upstream of or within macrophage migration IMP
IMP: 通过突变表型推断
15039218 MGI
acts upstream of or within negative regulation of epithelial cell proliferation IMP
IMP: 通过突变表型推断
9155011 MGI
acts upstream of or within oligosaccharide biosynthetic process IDA
IDA: 通过直接分析推断
9813328 MGI
acts upstream of or within penetration of zona pellucida IMP
IMP: 通过突变表型推断
9374408 MGI
acts upstream of or within positive regulation of apoptotic process IMP
IMP: 通过突变表型推断
15282149 MGI
acts upstream of or within positive regulation of epithelial cell proliferation involved in wound healing IMP
IMP: 通过突变表型推断
15039218 MGI
acts upstream of or within protein glycosylation IMP
IMP: 通过突变表型推断
9155011 MGI
acts upstream of or within regulation of acrosome reaction IMP
IMP: 通过突变表型推断
9374408 MGI
acts upstream of or within wound healing IMP
IMP: 通过突变表型推断
15039218 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in Golgi apparatus IDA
IDA: 通过直接分析推断
2503706 MGI
located in cell surface IDA
IDA: 通过直接分析推断
9374408 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
2503706 MGI
part of protein-containing complex IDA
IDA: 通过直接分析推断
11485999 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

beta-1,4-galactosyltransferase 1

N-acetyllactosamine synthase

UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 1

b1,4-Galactosyltransferase I

beta-1,4-GalTase 1

beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase

beta-N-acetylglucosaminylglycopep

相关产品

Pre-clinical Phase
生物活性分子 (6)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-E70289 Bovin beta-1,4-galactosyltransferase 1 (Y289L) / 否
HY-E70285 beta-1,4-Galactosyltransferase 1 (Y285L) / 否
HY-E70046 β-1,4-Galactosyltransferase, neisseria meningitides 90.00% 否
HY-RS01319 B4GALT1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18013 B4galt1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24486 B4galt1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens B4galt1 NCBI NCBI:2683
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