2. Gene
  3. CSRP2 - cysteine and glycine rich protein 2 Gene

CSRP2 - cysteine and glycine rich protein 2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：富半胱氨酸和甘氨酸的蛋白质 2

种属: Homo sapiens

同用名: CRP2; LMO5; SmLIM

基因 ID: 1466 | 基因类型: protein coding

关于 CSRP2

Cytogenetic location: 12q21.2 Genomic coordinates (GRCh38): 12:76,858,709-76,879,019 (from NCBI)

This gene has 7 transcripts (splice variants), 217 orthologues and 2 paralogues. Ubiquitous expression in esophagus (RPKM 37.2), placenta (RPKM 35.3) and 23 other tissues.

功能概要

CSRP2 是 CSRP 基因家族的成员，编码一组 LIM 结构域蛋白，可能参与对发育和细胞分化很重要的调节过程。 CRP2 包含两个拷贝的富含半胱氨酸的氨基酸序列基序 (LIM) ，具有推定的锌结合活性，并且可能参与调节有序细胞生长。该家族中的其他基因包括 CSRP1 和 CSRP3。可变剪接导致多个转录本变体。[RefSeq 提供，2014 年 7 月]

CSRP2 is a member of the CSRP family of genes, encoding a group of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. CRP2 contains two copies of the cysteine-rich amino acid sequence motif (LIM) with putative zinc-binding activity, and may be involved in regulating ordered cell growth. Other genes in the family include CSRP1 and CSRP3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

CSRP2 基因产物(9)

mRNA Protein Name
NM_001300965.2 NP_001287894.1 cysteine and glycine-rich protein 2 isoform b
NM_001321.3 NP_001312.1 cysteine and glycine-rich protein 2 isoform b
NM_001413535.1 NP_001400464.1 cysteine and glycine-rich protein 2 isoform b
NM_001413537.1 NP_001400466.1 cysteine and glycine-rich protein 2 isoform b
NM_001413538.1 NP_001400467.1 cysteine and glycine-rich protein 2 isoform b
NM_001413539.1 NP_001400468.1 cysteine and glycine-rich protein 2 isoform a
NM_001413540.1 NP_001400469.1 cysteine and glycine-rich protein 2 isoform c
NM_001413541.1 NP_001400470.1 cysteine and glycine-rich protein 2 isoform d
NM_001413542.1 NP_001400471.1 cysteine and glycine-rich protein 2 isoform e

CSRP2 蛋白结构

LIM

LIM: LIM domain (10 - 65)

LIM

LIM: LIM domain (119 - 175)

  • 0
  • 100
  • 193 a.a.
蛋白主名 其他名称

cysteine and glycine-rich protein 2

LIM domain only 5, smooth muscle

关联疾病

疾病名称 别名
Chromosome 8q21.11 Deletion Syndrome

8q21.11 Microdeletion Syndrome

Del(8)(Q21.11)

Deletion 8q21.11

Monosomy 8q21.11
Fanconi Anemia, Complementation Group C

Fanconi Anemia Complementation Group C

FANCC

Facc

Fac

Fa3

Fanconi Pancytopenia Type 3

Fanconi Pancytopenia, Type 3

Faces Syndrome

Facial Features , Anorexia, Cachexia, Eye And Skin Anomalies

Friedman-Goodman Syndrome

Abnormality Of The Face
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03259 CSRP2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta CSRP2 VGNC VGNC:71528
Rattus norvegicus CSRP2 RGD RGD:61950
Bos taurus CSRP2 VGNC VGNC:27774
Felis catus CSRP2 VGNC VGNC:83862
Mus musculus CSRP2 MGD MGI:1202907
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