2. Gene
  3. SLC25A10 - solute carrier family 25 member 10 Gene

SLC25A10 - solute carrier family 25 member 10 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：溶质载体家族 25 成员 10

种属: Homo sapiens

同用名: DIC; MTDPS19

基因 ID: 1468 | 基因类型: protein coding

关于 SLC25A10

Cytogenetic location: 17q25.3 Genomic coordinates (GRCh38): 17:81,712,284-81,721,012 (from NCBI)

This gene has 8 transcripts (splice variants), 237 orthologues, 49 paralogues and is associated with 1 phenotype. Broad expression in kidney (RPKM 33.1), liver (RPKM 15.3) and 20 other tissues.

功能概要

该基因编码一个蛋白质家族的成员，该蛋白质家族可将小代谢物转移到线粒体膜上。编码的蛋白质将苹果酸和琥珀酸等二羧酸盐交换为磷酸盐、硫酸盐和其他小分子，从而为包括三羧酸循环和脂肪酸合成在内的代谢过程提供底物。已经观察到该基因编码多种亚型的可变剪接转录物变体。[RefSeq 提供，2012 年 8 月]

This gene encodes a member of a family of proteins that translocate small metabolites across the mitochondrial membrane. The encoded protein exchanges dicarboxylates, such as malate and succinate, for phosphate, sulfate, and other small molecules, thereby providing substrates for metabolic processes including the Krebs cycle and fatty acid synthesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012]

SLC25A10 基因产物(3)

mRNA Protein Name
NM_001270888.2 NP_001257817.1 mitochondrial dicarboxylate carrier isoform 1
NM_001270953.2 NP_001257882.1 mitochondrial dicarboxylate carrier isoform 3
NM_012140.5 NP_036272.2 mitochondrial dicarboxylate carrier isoform 2

SLC25A10 蛋白结构

Mito_carr

Mito_carr: Mitochondrial carrier protein (11 - 91)

Mito_carr

Mito_carr: Mitochondrial carrier protein (97 - 189)

Mito_carr

Mito_carr: Mitochondrial carrier protein (198 - 281)

  • 0
  • 100
  • 200
  • 287 a.a.
蛋白主名 其他名称

mitochondrial dicarboxylate carrier

dicarboxylate ion carrier

关联疾病

疾病名称 别名
Mitochondrial Dna Depletion Syndrome 19

MTDPS19
Mitochondrial Complex I Deficiency, Nuclear Type 1

Mitochondrial Complex I Deficiency

Nadh:Q(1) Oxidoreductase Deficiency

MC1DN1

Nadh-Coenzyme Q Reductase Deficiency

Isolated Mitochondrial Respiratory Chain Complex I Deficiency

Isolated Nadh-Coenzyme Q Reductase Deficiency

Isolated Nadh-Coq Reductase Deficiency

Isolated Nadh-Ubiquinone Reductase Deficiency

Mitochondrial Nadh Dehydrogenase Component Of Complex I, Deficiency Of

Nuclear Type Mitochondrial Complex I Deficiency 1

Isolated Complex I Deficiency

Complex 1 Mitochondrial Respiratory Chain Deficiency

Nadh Coenzyme Q Reductase Deficiency

Complex I Mitochondrial Respiratory Chain Deficiency

Deficiency Of Mitochondrial Nadh Dehydrogenase Component Of Complex I

Nadh:Ubiquinone Oxidoreductase Deficiency

Complex I, Mitochondrial Respiratory Chain, Deficiency Of
Mitochondrial Dna Depletion Syndrome

Mtdna Depletion Syndrome
Early Infantile Epileptic Encephalopathy

Early Infantile Epileptic Encephalopathy With Burst-Suppression

Early Infantile Epileptic Encephalopathy With Suppression Bursts

Eiee

Early Infantile Epileptic Encephalopathy With Suppression-Bursts

Ohtahara Syndrome

Encephalopathy, Epileptic, Early Infantile
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13090 SLC25A10 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus SLC25A10 VGNC VGNC:107277
Felis catus SLC25A10 VGNC VGNC:99452
Mus musculus SLC25A10 MGD MGI:1353497
Rattus norvegicus SLC25A10 RGD RGD:621430
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