2. Gene
  3. Gnao1 - guanine nucleotide binding protein, alpha O Gene

Gnao1 - guanine nucleotide binding protein, alpha O Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Gnao; Hg1g; alphaO; Galphao

基因 ID: 14681 | 基因类型: protein coding

关于 Gnao1

功能概要

Enables GTP binding activity and GTPase activity. Acts upstream of or within several processes, including G protein-coupled receptor signaling pathway; Dopamine Receptor signaling pathway; and locomotory behavior. Located in cell body and dendrite. Is expressed in several structures, including alimentary system; brain; ganglia; genitourinary system; and sensory organ. Used to study developmental and epileptic encephalopathy 17 and neurodevelopmental disorder with involuntary movements. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 17 and neurodevelopmental disorder with involuntary movements. Orthologous to human GNAO1 (G protein subunit alpha o1). [provided by Alliance of Genome Resources, Apr 2022]

Gnao1 基因产物(2)

mRNA Protein Name
NM_001113384.1 NP_001106855.1 guanine nucleotide-binding protein G(o) subunit alpha isoform B
NM_010308.3 NP_034438.1 guanine nucleotide-binding protein G(o) subunit alpha isoform A
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables G protein activity IDA
IDA: 通过直接分析推断
10926822 MGI
enables GTP binding IMP
IMP: 通过突变表型推断
11248120 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
10926822 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within G protein-coupled dopamine receptor signaling pathway IMP
IMP: 通过突变表型推断
11248120 MGI
acts upstream of or within G protein-coupled receptor signaling pathway IMP
IMP: 通过突变表型推断
9501252 MGI
acts upstream of or within locomotory behavior IMP
IMP: 通过突变表型推断
9501252 MGI
involved in negative regulation of insulin secretion IMP
IMP: 通过突变表型推断
20622165 MGI
involved in postsynaptic modulation of chemical synaptic transmission IDA
IDA: 通过直接分析推断
33535037 MGI
involved in postsynaptic modulation of chemical synaptic transmission IMP
IMP: 通过突变表型推断
33535037 MGI
acts upstream of or within regulation of heart contraction IMP
IMP: 通过突变表型推断
9050846 MGI
acts upstream of negative effect vesicle docking involved in exocytosis IMP
IMP: 通过突变表型推断
20622165 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in GABA-ergic synapse IDA
IDA: 通过直接分析推断
34248508 MGI
located in cell body IDA
IDA: 通过直接分析推断
11685543 MGI
located in dendrite IDA
IDA: 通过直接分析推断
11685543 MGI
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
34248508 MGI
is active in parallel fiber to Purkinje cell synapse IDA
IDA: 通过直接分析推断
34248508 MGI
is active in postsynaptic membrane IDA
IDA: 通过直接分析推断
34248508 MGI
is active in presynaptic membrane IDA
IDA: 通过直接分析推断
34248508 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

guanine nucleotide-binding protein G(o) subunit alpha

GTP-binding protein alpha-o subunit

Go alpha

heterotrimeric guanine nucleotide-binding protein 1g

重组 Gnao1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P72207 GNAO1 Protein, Mouse (His) P18872 (G2-Y354) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05538 GNAO1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18822 Gnao1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25312 Gnao1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Gnao1 NCBI NCBI:2775
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z