2. Gene
  3. KCTD11 - potassium channel tetramerization domain containing 11 Gene

KCTD11 - potassium channel tetramerization domain containing 11 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：含钾通道四聚结构域 11

种属: Homo sapiens

同用名: REN; KCASH1; C17orf36; REN/KCTD11

基因 ID: 147040 | 基因类型: protein coding

关于 KCTD11

Cytogenetic location: 17p13.1 Genomic coordinates (GRCh38): 17:7,352,162-7,354,944 (from NCBI)

This gene has 2 transcripts (splice variants), 1 gene allele, 96 orthologues and 13 paralogues.

功能概要

实现相同的蛋白质结合活性。预计参与神经元分化的正调控。预计在成神经细胞增殖的负调节和平滑信号通路的负调节的上游或内部起作用。预计位于细胞质中。 [由基因组资源联盟提供，2022 年 4 月]

Enables identical protein binding activity. Predicted to be involved in positive regulation of neuron differentiation. Predicted to act upstream of or within negative regulation of neuroblast proliferation and negative regulation of smoothened signaling pathway. Predicted to be located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

KCTD11 基因产物(2)

mRNA Protein Name
NM_001002914.3 NP_001002914.1 BTB/POZ domain-containing protein KCTD11 s
NM_001363642.1 NP_001350571.1 BTB/POZ domain-containing protein KCTD11 l
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IPI
IPI: 通过物理相互作用推断
27152988 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

KCTD11 蛋白结构

BTB_2

BTB_2: BTB/POZ domain (21 - 69)

  • 0
  • 100
  • 200
  • 232 a.a.
蛋白主名 其他名称

BTB/POZ domain-containing protein KCTD11

RING-type E3 ubiquitin transferase subunit KCTD11

KCTD11 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
KCTD11 Q693B1 KCTD11 Homo sapiens Q693B1
GMS
27152988
种属内
KCTD11 Q693B1 KCTD11 Homo sapiens Q693B1
EM
27152988
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Medulloblastoma

MDB

Cpnet

Localized Primitive Neuroectodermal Tumor

Classic Medulloblastoma

Medulloblastoma Predisposition Syndrome

Medulloblastoma, Somatic

Brain Medulloblastoma

Cns Pnet

Infratentorial Primitive Neuroectodermal Tumor

Neuroectodermal Tumors, Primitive

Medulloblastomas

Desmoplastic Medulloblastoma

Medulloblastoma, With Extensive Nodularity

Medulloblastoma Of Unspecified Site

Medullomyoblastoma Of Unspecified Site
Scalp-Ear-Nipple Syndrome

Finlay-Marks Syndrome

Sen Syndrome

SENS

Scalp Ear Nipple Syndrome

Hereditary Syndrome Of Lumpy Scalp, Odd Ears And Rudimentary Nipples

Hereditary Syndrome Of Lumpy Scalp, Odd Ears, And Rudimentary Nipples

Indian Childhood Cirrhosis
Progressive Myoclonus Epilepsy

Pme

Progressive Myoclonic Epilepsy

Myoclonic Epilepsies, Progressive

Unverricht-Lundborg Syndrome
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07188 KCTD11 Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus KCTD11 MGD MGI:2448712
Macaca mulatta KCTD11 VGNC VGNC:99161
Rattus norvegicus KCTD11 RGD RGD:1307125
Bos taurus KCTD11 VGNC VGNC:30501
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