HIPK4 - homeodomain interacting protein kinase 4 Gene

中文名称：同源结构域相互作用蛋白激酶 4

种属: Homo sapiens

关于 HIPK4

功能概要

该基因编码同源域相互作用蛋白激酶 (HIPK) 蛋白家族的成员。虽然这个家族的其他成员遍布脊椎动物，但这个成员只存在于哺乳动物中。与该家族的其他成员相比，编码的蛋白质缺乏核定位信号和 C 端自抑制结构域。编码的蛋白质表现出激酶活性，并可能使肿瘤抑制蛋白 p53 磷酸化。[RefSeq 提供，2016 年 7 月]

This gene encodes a member of the homeodomain interacting protein kinase (HIPK) family of proteins. While Other members of this family are found throughout vertebrates, this member is present only in mammals. Compared to Other members of this family, the encoded protein lacks a nuclear localization signal and a C-terminal autoinhibitory domain. The encoded protein exhibits kinase activity and may phosphorylate the tumor suppressor protein p53. [provided by RefSeq, Jul 2016]