1. Gene
  2. DTX3L - deltex E3 ubiquitin ligase 3L Gene

DTX3L - deltex E3 ubiquitin ligase 3L Gene

中文名称:deltex E3 泛素连接酶 3L

种属: Homo sapiens

同用名: BBAP; RNF143

基因 ID: 151636 | 基因类型: protein coding

关于 DTX3L

Cytogenetic location: 3q21.1 Genomic coordinates (GRCh38): 3:122,564,338-122,575,203 (from NCBI)

This gene has 2 transcripts (splice variants), 355 orthologues and 4 paralogues. Ubiquitous expression in appendix (RPKM 14.2), spleen (RPKM 13.2) and 25 other tissues.

功能概要

DTX3L 作为 E3 泛素连接酶发挥作用 (Takeyama 等人,2003 [PubMed 12670957]) 。[OMIM 提供,2009 年 11 月]

DTX3L functions as an E3 ubiquitin ligase (Takeyama et al., 2003 [PubMed 12670957]).[supplied by OMIM, Nov 2009]

DTX3L 基因产物(1)

mRNA Protein Name
NM_138287.3 NP_612144.1 E3 ubiquitin-protein ligase DTX3L

DTX3L 蛋白结构

zf-RING_2

zf-RING_2: Ring finger domain (560 - 599)

  • 0
  • 200
  • 400
  • 600
  • 740 a.a.
蛋白主名 其他名称

E3 ubiquitin-protein ligase DTX3L

B-lymphoma- and BAL-associated protein

关联疾病

疾病名称 别名
Arteriovenous Malformations Of The Brain

Cerebral Arteriovenous Malformation

Intracranial Arteriovenous Malformation

Intracranial Hemorrhage In Brain Cerebrovascular Malformations, Susceptibility To

Intracranial Arteriovenous Malformations

Bavm

Cerebral Arteriovenous Malformations

Intracranial Hemorrhage In Brain Cerebrovascular Malformations

Arteriovenous Malformation Of The Brain, Somatic

Intracranial Avm

Arteriovenous Malformations Cerebral

Primary Autosomal Recessive Microcephaly

Autosomal Recessive Primary Microcephaly

Mcph

True Microcephaly

Microcephalia Vera

Microcephaly Vera

Microcephaly Primary Hereditary

Microcephaly, Primary, Autosomal Recessive

Primary Microcephaly

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus DTX3L RGD RGD:1565144
Macaca mulatta DTX3L VGNC VGNC:71995
Felis catus DTX3L VGNC VGNC:61651
Canis familiaris DTX3L VGNC VGNC:40118
Mus musculus DTX3L MGD MGI:2656973
Bos taurus DTX3L VGNC VGNC:28239
Others DTX3L NCBI