2. Gene
  3. MBLAC2 - metallo-beta-lactamase domain containing 2 Gene

MBLAC2 - metallo-beta-lactamase domain containing 2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：含金属-β-内酰胺酶结构域 2

种属: Homo sapiens

基因 ID: 153364 | 基因类型: protein coding

关于 MBLAC2

This gene has 2 transcripts (splice variants), 199 orthologues and 4 paralogues. Ubiquitous expression in brain (RPKM 4.5), ovary (RPKM 4.5) and 25 other tissues.

功能概要

启用棕榈酰辅酶 A 水解酶活性。位于内质网膜和质膜。 [由基因组资源联盟提供，2022 年 4 月]

Enables palmitoyl-CoA hydrolase activity. Located in endoplasmic reticulum membrane and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

MBLAC2 基因产物(1)

mRNA Protein Name
NM_203406.2 NP_981951.2 acyl-coenzyme A thioesterase MBLAC2
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables beta-lactamase activity IDA
IDA: 通过直接分析推断
31434986 GOA
enables long-chain fatty acyl-CoA hydrolase activity IMP
IMP: 通过突变表型推断
33219126 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in endoplasmic reticulum membrane IDA
IDA: 通过直接分析推断
33219126 GOA
located in plasma membrane IDA
IDA: 通过直接分析推断
33219126 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

MBLAC2 蛋白结构

Lactamase_B

Lactamase_B: Metallo-beta-lactamase superfamily (30 - 218)

  • 0
  • 100
  • 200
  • 279 a.a.
蛋白主名 其他名称

acyl-coenzyme A thioesterase MBLAC2

acyl-CoA thioesterase MBLAC2

MBLAC2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
MBLAC2 Q68D91 PBX3 Homo sapiens Q96AL5
Validated Y2H
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Jalili Syndrome

Cone-Rod Dystrophy And Amelogenesis Imperfecta

Cone Rod Dystrophy-Amelogenesis Imperfecta Syndrome

Cone-Rod Dystrophy Amelogenesis Imperfecta

Cone-Rod Dystrophy With Amelogenesis Imperfecta

JALIS

Cone Rod Dystrophy Amelogenesis Imperfecta
Usher Syndrome, Type Iic

Usher Syndrome Type 2c

USH2C

Usher Syndrome, Type 2c

Usher Syndrome, Type Iic, Gpr98/Pdzd7 Digenic

Usher Syndrome Type Iic

Usher Syndrome, Type 2c, Gpr98/Pdzd7 Digenic

Usher Syndrome 2c

Usher'S Syndrome Type 2c

Usher Syndrome Type Iic Gpr98/Pdzd7 Digenic
Tetralogy Of Fallot

TOF

Fallot Tetralogy

Ventricular Septal Defect With Pulmonary Stenosis Or Atresia, Dextraposition Of Aorta, And Hypertrophy Of Right Ventricle

Tetrad Of Fallot

Fallot Tetrad

Fallot Disease

Fallot Complex

Subpulmonic Stenosis, Ventricular Septal Defect, Overriding Aorta, And Right Ventricular Hypertrophy

Interventricular Septal Defect With Dextroposition Of Aorta, Pulmonary Stenosis And Hypertrophy Of Right Ventricle

Interventricular Septal Defect, In Tetralogy Of Fallot

Ventricular Septal Defect With Obstructed Right Ventricular Outflow

Tof - [Tetralogy Of Fallot]

Pulmonary Atresia With Ventricular Septal Defect [Fallot Type]

Pulmonary Atresia, Ventricular Septal Defect And Mapcas

Pulmonary Atresia With Ventricular Septal Defect And Systemic-To-Pulmonary Collateral Arteries [Fallot Type]
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Approval
生物活性分子 (2)
目录号 产品名 作用方式
纯度 是否罕见病
HY-13322 Pracinostat 99.80% 是
HY-105246 Pracinostat dihydrochloride / 否
Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-10990 Abexinostat Inhibitor 99.00% Phase 3
Pre-clinical Phase
生物活性分子 (11)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-13271A Tubastatin A 98.37% 否
HY-13428 Tubacin Inhibitor 99.54% 否
HY-13271 Tubastatin A Hydrochloride 99.31% 否
HY-19328 ACY-775 Inhibitor 99.71% 否
HY-100871 WT-161 98.36% 否
HY-13271B Tubastatin A TFA / 否
HY-13271AG Tubastatin A (GMP) / 否
HY-RS08189 MBLAC2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-110061 (2R,4R,6S)-Tubacin Control / 否
HY-RS18425 Mblac2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24906 Mblac2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta MBLAC2 VGNC VGNC:110452
Mus musculus MBLAC2 MGD MGI:1920102
Bos taurus MBLAC2 VGNC VGNC:31282
Felis catus MBLAC2 VGNC VGNC:63400
Canis familiaris MBLAC2 VGNC VGNC:43056
Rattus norvegicus MBLAC2 RGD RGD:1306703
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