Hsp90ab1 - heat shock protein 90 alpha (cytosolic), class B member 1 Gene

种属: Mus musculus

同用名: 90kDa; Hsp84; Hsp90; Hspcb; Hsp84-1

关于 Hsp90ab1

功能概要

Enables protein folding chaperone; protein kinase binding activity; and Tau Protein binding activity. Contributes to protein kinase regulator activity. Involved in several processes, including axonogenesis; positive regulation of protein kinase B signaling; and regulation of cellular protein metabolic process. Acts upstream of or within cellular response to interleukin-4; negative regulation of apoptotic process; and placenta development. Located in growth cone; neuronal cell body; and perinuclear region of cytoplasm. Part of HSP90-CDC37 chaperone complex. Is expressed in several structures, including branchial arch; central nervous system; eye; limb; and placenta. Human ortholog(s) of this gene implicated in multiple sclerosis. Orthologous to human HSP90AB1 (heat shock protein 90 alpha family class B member 1). [provided by Alliance of Genome Resources, Apr 2022]