CYP2F1 - cytochrome P450 family 2 subfamily F member 1 Gene

中文名称：细胞色素 P450 家族 2 亚家族 F 成员 1

种属: Homo sapiens

同用名: C2F1; CYP2F; CYPIIF1

关于 CYP2F1

功能概要

该基因编码细胞色素 P450 酶超家族的成员。细胞色素 P450 蛋白是单加氧酶，可催化许多涉及药物代谢和胆固醇、类固醇和其他脂质合成的反应。这种蛋白质定位于内质网，已知可使 3-甲基吲哚脱氢，这是一种源自色氨酸发酵的内源性毒素，以及萘和乙氧基香豆素等外源底物。该基因是来自 19q 染色体上 CYP2A、CYP2B 和 CYP2F 亚家族的一大群细胞色素 P450 基因的一部分。[RefSeq 提供，2008 年 7 月]

This gene encodes a member of the Cytochrome P450 superfamily of Enzymes. The Cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of Cholesterol, Steroids and Other lipids. This protein localizes to the endoplasmic reticulum and is known to dehydrogenate 3-methylindole, an endogenous toxin derived from the fermentation of tryptophan, as well as xenobiotic substrates such as naphthalene and ethoxycoumarin. This gene is part of a large cluster of Cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. [provided by RefSeq, Jul 2008]