2. Gene
  3. Igfbp3 - insulin-like growth factor binding protein 3 Gene

Igfbp3 - insulin-like growth factor binding protein 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: IGFBP-3; IGgfbp3

基因 ID: 16009 | 基因类型: protein coding

关于 Igfbp3

功能概要

Enables fibronectin binding activity and insulin-like growth factor binding activity. Acts upstream of or within several processes, including osteoblast differentiation; positive regulation of signal transduction; and type B pancreatic cell proliferation. Located in extracellular space. Is expressed in several structures, including alimentary system; brain; early embryo; gonad; and limb. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Turner syndrome; diabetes mellitus (multiple); prostate cancer; and transitional cell carcinoma. Orthologous to human IGFBP3 (Insulin like growth factor binding protein 3). [provided by Alliance of Genome Resources, Apr 2022]

Igfbp3 基因产物(1)

mRNA Protein Name
NM_008343.2 NP_032369.2 insulin-like growth factor-binding protein 3 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables fibronectin binding IDA
IDA: 通过直接分析推断
19236847 MGI
enables insulin-like growth factor binding IPI
IPI: 通过物理相互作用推断
7679139 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of MAPK cascade IGI
IGI: 通过遗传相互作用推断
16675541 MGI
involved in osteoblast differentiation IEP
IEP: 通过表达模式推断
16311053 MGI
acts upstream of or within positive regulation of MAPK cascade IGI
IGI: 通过遗传相互作用推断
16675541 MGI
acts upstream of or within positive regulation of insulin-like growth factor receptor signaling pathway IGI
IGI: 通过遗传相互作用推断
16675541 MGI
acts upstream of or within regulation of cell growth IGI
IGI: 通过遗传相互作用推断
16675541 MGI
acts upstream of or within regulation of glucose metabolic process IGI
IGI: 通过遗传相互作用推断
16675541 MGI
acts upstream of or within regulation of growth IGI
IGI: 通过遗传相互作用推断
16675541 MGI
acts upstream of or within type B pancreatic cell proliferation IGI
IGI: 通过遗传相互作用推断
16675541 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
7510770 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

insulin-like growth factor-binding protein 3

IBP-3

IGF-binding protein 3

相关产品

Pre-clinical Phase
生物活性分子 (7)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-W074890 Palmitoylglycine Modulator 99.84% 否
HY-110135A NBI-31772 hydrate Inhibitor 99.42% 否
HY-N3316 Martynoside Antagonist 99.41% 否
HY-RS06626 IGFBP3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-P10403 IGFBP-3 peptide / 否
HY-RS17430 Igfbp3 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23885 Igfbp3 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Igfbp3 NCBI NCBI:3486
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