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  3. Il1r2 - interleukin 1 receptor, type II Gene

Il1r2 - interleukin 1 receptor, type II Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: CD121b; Il1r-2

基因 ID: 16178 | 基因类型: protein coding

关于 Il1r2

功能概要

Enables interleukin-1 binding activity and interleukin-1 receptor activity. Acts upstream of or within negative regulation of gene expression and negative regulation of interleukin-1-mediated signaling pathway. Located in cytoplasm. Is expressed in several structures, including dorsal aorta; gut; pituitary gland; reproductive system; and thymus. Human ortholog(s) of this gene implicated in aggressive periodontitis. Orthologous to human IL1R2 (interleukin 1 receptor type 2). [provided by Alliance of Genome Resources, Apr 2022]

Il1r2 基因产物(3)

mRNA Protein Name
NM_001360800.1 NP_001347729.1 interleukin-1 receptor type 2 isoform 1 precursor
NM_001360801.1 NP_001347730.1 interleukin-1 receptor type 2 isoform 3
NM_010555.5 NP_034685.1 interleukin-1 receptor type 2 isoform 2 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables interleukin-1 binding IPI
IPI: 通过物理相互作用推断
23395675 MGI
enables interleukin-1 receptor activity IPI
IPI: 通过物理相互作用推断
23395675 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within negative regulation of cytokine production involved in inflammatory response IMP
IMP: 通过突变表型推断
23395675 MGI
acts upstream of or within negative regulation of interleukin-1 alpha production IMP
IMP: 通过突变表型推断
23395675 MGI
acts upstream of or within negative regulation of interleukin-1-mediated signaling pathway IPI
IPI: 通过物理相互作用推断
23395675 MGI
acts upstream of or within negative regulation of protein processing IMP
IMP: 通过突变表型推断
23395675 MGI
acts upstream of protein processing IMP
IMP: 通过突变表型推断
23395675 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
23395675 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

interleukin-1 receptor type 2

CD121 antigen-like family member B

IL-1 receptor beta chain

IL-1 type II receptor

IL-1R-2

IL-1R-beta

IL-1RT-2

IL-1RT2

interleukin-1 receptor beta

重组 Il1r2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P72568 IL-1R2 Protein, Mouse (HEK293, His) P27931 (F14-E355) ≥95%
HY-P74820 IL-1R2 Protein, Mouse (HEK293, hFc) P27931 (F14-E355) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06721 IL1R2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19694 Il1r2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26189 Il1r2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Il1r2 NCBI NCBI:7850
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