CNST - consortin, connexin sorting protein Gene

中文名称：consortin，连接蛋白分选蛋白

种属: Homo sapiens

同用名: C1orf71; PPP1R64

关于 CNST

功能概要

许多跨膜蛋白靶向细胞表面被认为取决于它们被货物受体识别，这些受体与适配器机制相互作用，用于高尔基复合体远端的顺行交通。 Consortin (CNST) 是一种完整的膜蛋白，作为连接蛋白的结合伙伴，缝隙连接的构建块，并作为一种反式高尔基体网络 (TGN) 受体参与连接蛋白靶向质膜和从细胞回收表面 (del Castillo 等人，2010 [PubMed 19864490]) 。[OMIM 提供，2010 年 6 月]

Targeting of numerous transmembrane proteins to the cell surface is thought to depend on their recognition by cargo receptors that interact with the adaptor machinery for anterograde traffic at the distal end of the Golgi complex. Consortin (CNST) is an integral membrane protein that acts as a binding partner of connexins, the building blocks of gap junctions, and acts as a trans-Golgi network (TGN) receptor involved in connexin targeting to the plasma membrane and recycling from the cell surface (del Castillo et al., 2010 [PubMed 19864490]).[supplied by OMIM, Jun 2010]