2. Gene
  3. Lat - linker for activation of T cells Gene

Lat - linker for activation of T cells Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: pp36; p36-38

基因 ID: 16797 | 基因类型: protein coding

关于 Lat

功能概要

Predicted to enable protein kinase binding activity and signaling receptor complex adaptor activity. Acts upstream of or within gene expression; inflammatory response; and lymphocyte homeostasis. Located in cell-cell junction and immunological synapse. Part of COP9 signalosome. Is expressed in liver and thymus primordium. Used to study IgG4-related disease. Human ortholog(s) of this gene implicated in immunodeficiency 52. Orthologous to human LAT (linker for activation of T cells). [provided by Alliance of Genome Resources, Apr 2022]

Lat 基因产物(1)

mRNA Protein Name
NM_010689.3 NP_034819.1 linker for activation of T-cells family member 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
21487392 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within gene expression IMP
IMP: 通过突变表型推断
16002666 MGI
acts upstream of or within homeostasis of number of cells IMP
IMP: 通过突变表型推断
23793062 MGI
acts upstream of or within inflammatory response IMP
IMP: 通过突变表型推断
16002666 MGI
acts upstream of or within lymphocyte homeostasis IMP
IMP: 通过突变表型推断
23776175 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of COP9 signalosome IDA
IDA: 通过直接分析推断
22561606 MGI
located in cell-cell junction IDA
IDA: 通过直接分析推断
23793062 MGI
located in immunological synapse IDA
IDA: 通过直接分析推断
14635057 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

linker for activation of T-cells family member 1

36 kDa phospho-tyrosine adapter protein

linker protein

相关产品

Clinical Phase
生物活性分子 (2)
目录号 产品名 作用方式
纯度 Phase
HY-16929 Latrunculin A Inhibitor 98.9% Phase 4
HY-164401 QBS10072S / Phase 2
Pre-clinical Phase
生物活性分子 (30)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-138489 TRULI Modulator 99.98% 否
HY-150042 TDI-011536 Inhibitor 99.91% 否
HY-108540 BCH Inducer 99.13% 否
HY-147082 GA-017 Activator 98.95% 否
HY-W011391 GPNA hydrochloride 99.91% 否
HY-160769 NIBR-LTSi Activator 99.97% 否
HY-139330 MGH-CP1 Inducer 99.56% 否
HY-W087830 L-p-Boronophenylalanine 99.66% 否
HY-147165 VT02956 Inhibitor 99.58% 否
HY-120139 KMH-233 Inhibitor 99.75% 否
HY-130504 Propargyl-PEG1-acid ≥97.0% 否
HY-N8847 α-Ionone Activator 94.30% 否
HY-N3999 Venuloside A 99.82% 否
HY-120139A (R)-KMH-233 Control / 否
HY-127042 6,7-Epoxy-latrunculin A Inhibitor / 否
HY-129934S Latanoprost ethyl amide-d4 / 否
HY-RS07536 LAT Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS07537 LAT2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS07538 LATS1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS07539 LATS2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS09827 ORC3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS13690 SPNS1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-147165A VT02956 hydrochloride Inhibitor / 否
HY-RS16816 Lat Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17343 Lats1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18181 Lats2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21361 Lat2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23256 Lat Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23797 Lats1 Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24655 Lats2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Lat NCBI NCBI:27040
Canis familiaris Lat NCBI NCBI:607947
Felis catus Lat NCBI NCBI:101093319
Macaca fascicularis Lat NCBI NCBI:102143768
Canis lupus familiaris Lat NCBI
Susscrofa domestica Lat NCBI
Leporidae Lat NCBI
Rattus norvegicus Lat NCBI NCBI:81511
Macaca mulatta Lat NCBI NCBI:704656
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z