2. Gene
  3. Lhcgr - luteinizing hormone/choriogonadotropin receptor Gene

Lhcgr - luteinizing hormone/choriogonadotropin receptor Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Lhr; LH-R; LSH-R; LH/CG-R; Gpcr19-rs1

基因 ID: 16867 | 基因类型: protein coding

关于 Lhcgr

功能概要

Enables choriogonadotropin hormone binding activity and choriogonadotropin hormone receptor activity. Involved in several processes, including G protein-coupled receptor signaling pathway; activation of Adenylate Cyclase activity; and positive regulation of inositol trisphosphate biosynthetic process. Acts upstream of or within several processes, including development of secondary male sexual characteristics; regulation of steroid hormone biosynthetic process; and reproductive structure development. Is integral component of plasma membrane. Is expressed in early conceptus; medulla oblongata; medulla oblongata basal plate ventricular layer; oocyte; and testis. Human ortholog(s) of this gene implicated in Leydig cell hypoplasia; Leydig cell tumor; breast cancer; familial male-limited precocious puberty; and gonadal disease. Orthologous to human LHCGR (luteinizing hormone/choriogonadotropin receptor). [provided by Alliance of Genome Resources, Apr 2022]

Lhcgr 基因产物(2)

mRNA Protein Name
NM_001364898.1 NP_001351827.1 lutropin-choriogonadotropic hormone receptor isoform 2 precursor
NM_013582.3 NP_038610.1 lutropin-choriogonadotropic hormone receptor isoform 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables choriogonadotropin hormone binding IDA
IDA: 通过直接分析推断
10493819 MGI
enables choriogonadotropin hormone receptor activity IDA
IDA: 通过直接分析推断
10493819 MGI
enables choriogonadotropin hormone receptor activity IMP
IMP: 通过突变表型推断
11145748 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in activation of adenylate cyclase activity IDA
IDA: 通过直接分析推断
10493819 MGI
involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway IDA
IDA: 通过直接分析推断
10493819 MGI
involved in cellular response to gonadotropin stimulus IDA
IDA: 通过直接分析推断
10493819 MGI
acts upstream of or within development of secondary male sexual characteristics IMP
IMP: 通过突变表型推断
11145748 MGI
acts upstream of or within female gonad development IMP
IMP: 通过突变表型推断
11145748 MGI
acts upstream of or within male gonad development IMP
IMP: 通过突变表型推断
11145748 MGI
acts upstream of or within ovarian follicle development IMP
IMP: 通过突变表型推断
11145748 MGI
acts upstream of or within ovulation cycle process IMP
IMP: 通过突变表型推断
11145748 MGI
involved in phospholipase C-activating G protein-coupled receptor signaling pathway IDA
IDA: 通过直接分析推断
10493819 MGI
involved in positive regulation of inositol trisphosphate biosynthetic process IDA
IDA: 通过直接分析推断
10493819 MGI
acts upstream of or within regulation of steroid hormone biosynthetic process IMP
IMP: 通过突变表型推断
11145748 MGI
acts upstream of or within seminiferous tubule development IMP
IMP: 通过突变表型推断
11145748 MGI
acts upstream of or within spermatogenesis IMP
IMP: 通过突变表型推断
11145748 MGI
acts upstream of or within uterus development IMP
IMP: 通过突变表型推断
11145748 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in plasma membrane IDA
IDA: 通过直接分析推断
10493819 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

lutropin-choriogonadotropic hormone receptor

相关产品

Pre-clinical Phase
生物活性分子 (6)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-150210 FSHR agonist 1 Agonist 99.45% 否
HY-100271 Org41841 Agonist 99.77% 否
HY-RS07624 LHCGR Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-P10594 Myr-Arf1(2–17) / 否
HY-RS17915 Lhcgr Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24384 Lhcgr Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Lhcgr NCBI NCBI:3973
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z