1. Gene
  2. IDO2 - indoleamine 2,3-dioxygenase 2 Gene

IDO2 - indoleamine 2,3-dioxygenase 2 Gene

中文名称:吲哚胺 2,3-双加氧酶 2

种属: Homo sapiens

同用名: INDOL1

基因 ID: 169355 | 基因类型: protein coding

关于 IDO2

Cytogenetic location: 8p11.21 Genomic coordinates (GRCh38): 8:39,934,651-40,016,392 (from NCBI)

This gene has 3 transcripts (splice variants) and 91 orthologues. Biased expression in placenta (RPKM 9.5), liver (RPKM 2.8) and 3 other tissues.

功能概要

与 INDO (MIM 147435) 和 TDO2 (MIM 191070) 基因编码的酶一起,INDOL1 基因编码的酶在犬尿氨酸途径中代谢色氨酸 (Ball 等人,2007 [PubMed 17499941]) 。[OMIM 提供, 2011 年 2 月]

Along with the enzymes encoded by the INDO (MIM 147435) and TDO2 (MIM 191070) genes, the Enzyme encoded by the INDOL1 gene metabolizes tryptophan in the kynurenine pathway (Ball et al., 2007 [PubMed 17499941]).[supplied by OMIM, Feb 2011]

IDO2 基因产物(2)

mRNA Protein Name
NM_194294.5 NP_919270.3 indoleamine 2,3-dioxygenase 2
NM_001395206.1 NP_001382135.1 indoleamine 2,3-dioxygenase 2

IDO2 蛋白结构

IDO

IDO: Indoleamine 2,3-dioxygenase (14 - 401)

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  • 200
  • 300
  • 407 a.a.
蛋白主名 其他名称

indoleamine 2,3-dioxygenase 2

indoleamine 2,3-dioxygenase-like 1 protein

indoleamine 2,3-dioxygenase-like protein 1

indoleamine-pyrrole 2,3 dioxygenase-like 1

indoleamine-pyrrole 2,3-dioxygenase-like protein 1

重组 IDO2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70863 IDO-2 Protein, Human (His) Q6ZQW0 (M14-G420) ≥95%
HY-P71743 IDO-2 Protein, Human (P.pastoris, His) Q6ZQW0 (14M-420G) ≥95%

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus IDO2 RGD RGD:1596771
Bos taurus IDO2 VGNC VGNC:30036
Mus musculus IDO2 MGD MGI:2142489
Canis familiaris IDO2 VGNC VGNC:41866
Macaca mulatta IDO2 VGNC VGNC:84005
Felis catus IDO2 VGNC VGNC:78513
Others IDO2 NCBI