2. Gene
  3. Zbtb7a - zinc finger and BTB domain containing 7a Gene

Zbtb7a - zinc finger and BTB domain containing 7a Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Lrf; FBI-1; Zbtb7; Pokemon; 9030619K07Rik; 9130006G12Rik

基因 ID: 16969 | 基因类型: protein coding

关于 Zbtb7a

功能概要

Enables DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and Histone Acetyltransferase binding activity. Involved in several processes, including hemopoiesis; nucleic acid metabolic process; and regulation of transcription, DNA-templated. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Part of DNA-dependent protein kinase complex. Colocalizes with site of double-strand break. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; hemolymphoid system; and retina. Orthologous to human ZBTB7A (zinc finger and BTB domain containing 7A). [provided by Alliance of Genome Resources, Apr 2022]

Zbtb7a 基因产物(8)

mRNA Protein Name
NM_001404861.1 NP_001391790.1 zinc finger and BTB domain-containing protein 7A
NM_001404862.1 NP_001391791.1 zinc finger and BTB domain-containing protein 7A
NM_001404863.1 NP_001391792.1 zinc finger and BTB domain-containing protein 7A
NM_001404864.1 NP_001391793.1 zinc finger and BTB domain-containing protein 7A
NM_001404865.1 NP_001391794.1 zinc finger and BTB domain-containing protein 7A
NM_001404866.1 NP_001391795.1 zinc finger and BTB domain-containing protein 7A
NM_001404867.1 NP_001391796.1 zinc finger and BTB domain-containing protein 7A
NM_010731.4 NP_034861.3 zinc finger and BTB domain-containing protein 7A
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA binding IDA
IDA: 通过直接分析推断
15337766 MGI
enables DNA-binding transcription factor activity IDA
IDA: 通过直接分析推断
15662416 MGI
enables DNA-binding transcription factor activity IMP
IMP: 通过突变表型推断
29813070 MGI
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
15337766 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
15337766 MGI
enables histone acetyltransferase binding IPI
IPI: 通过物理相互作用推断
15337766 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
15337766 MGI
enables sequence-specific DNA binding IDA
IDA: 通过直接分析推断
15662416 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in B cell differentiation IMP
IMP: 通过突变表型推断
17495164 MGI
involved in DNA-templated transcription IMP
IMP: 通过突变表型推断
29813070 MGI
involved in chromatin organization IMP
IMP: 通过突变表型推断
29813070 MGI
involved in double-strand break repair via classical nonhomologous end joining IDA
IDA: 通过直接分析推断
26446488 MGI
involved in erythrocyte maturation IMP
IMP: 通过突变表型推断
26816381 MGI
involved in negative regulation of DNA-templated transcription IMP
IMP: 通过突变表型推断
15337766 MGI
involved in negative regulation of Notch signaling pathway IMP
IMP: 通过突变表型推断
17495164 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
15662416 MGI
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
15337766 MGI
involved in regulation of DNA-binding transcription factor activity IMP
IMP: 通过突变表型推断
29813070 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of DNA-dependent protein kinase complex IMP
IMP: 通过突变表型推断
26446488 MGI
colocalizes with site of double-strand break IDA
IDA: 通过直接分析推断
26446488 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

zinc finger and BTB domain-containing protein 7A

POK erythroid myeloid ontogenic factor

POZ and Krueppel erythroid myeloid ontogenic factor

leukemia/lymphoma related factor

Zbtb7a 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Zbtb7a O88939 Hdac1 Mus musculus O09106
Anti Tag CoIP
26816381
种属内
Zbtb7a O88939 Hdac1 Mus musculus O09106
Anti Bait CoIP
15337766
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-152775 RK-701 Inhibitor 98.04% 否
HY-RS15979 ZBTB7A Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19274 Zbtb7a Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25763 Zbtb7a Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Zbtb7a NCBI NCBI:51341
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