2. Gene
  3. Lonp1 - lon peptidase 1, mitochondrial Gene

Lonp1 - lon peptidase 1, mitochondrial Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Lon; Prss15

基因 ID: 170916 | 基因类型: protein coding

关于 Lonp1

功能概要

Enables ATP-dependent peptidase activity. Involved in several processes, including aging; response to aluminum ion; and response to hypoxia. Located in mitochondrial matrix. Used to study brain ischemia and ischemia. Human ortholog(s) of this gene implicated in CODAS syndrome. Orthologous to human LONP1 (lon peptidase 1, mitochondrial). [provided by Alliance of Genome Resources, Apr 2022]

Lonp1 基因产物(1)

mRNA Protein Name
NM_133404.1 NP_596895.1 lon protease homolog, mitochondrial precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ATP-dependent peptidase activity IDA
IDA: 通过直接分析推断
12752449 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in mitochondrion organization IEP
IEP: 通过表达模式推断
10050756 RGD
involved in protein catabolic process IDA
IDA: 通过直接分析推断
12752449 RGD
involved in protein-containing complex assembly IMP
IMP: 通过突变表型推断
12082077 RGD
involved in response to aluminum ion IEP
IEP: 通过表达模式推断
19010380 RGD
involved in response to hormone IEP
IEP: 通过表达模式推断
10050756 RGD
involved in response to hypoxia IEP
IEP: 通过表达模式推断
12082077 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrial matrix IDA
IDA: 通过直接分析推断
15560797 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

lon protease homolog, mitochondrial

LONP

lon protease-like protein

mitochondrial ATP-dependent protease Lon

protease, serine, 15

serine protease 15

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-153034 LONP1-IN-2 99.74% 否
HY-158412 BT317 99.81% 否
HY-RS07734 LONP1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18289 Lonp1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24767 Lonp1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Lonp1 NCBI NCBI:9361
Mus musculus Lonp1 NCBI NCBI:74142
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