1. Gene
  2. Masp1 - mannan-binding lectin serine peptidase 1 Gene

Masp1 - mannan-binding lectin serine peptidase 1 Gene

种属: Mus musculus

同用名: CCPII; Crarf; Masp1/3

基因 ID: 17174 | 基因类型: protein coding

关于 Masp1

功能概要

Enables serine-type endopeptidase activity. Involved in complement activation, lectin pathway. Located in extracellular space. Is expressed in several structures, including alimentary system; brain; genitourinary system; liver; and spleen. Human ortholog(s) of this gene implicated in 3MC syndrome 1. Orthologous to human MASP1 (MBL associated serine protease 1). [provided by Alliance of Genome Resources, Apr 2022]

Masp1 基因产物(2)

mRNA Protein Name
NM_001359083.1 NP_001346012.1 mannan-binding lectin serine protease 1 isoform 1 precursor
NM_008555.3 NP_032581.2 mannan-binding lectin serine protease 1 isoform 2 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables serine-type endopeptidase activity IDA
IDA: 通过直接分析推断
18424734 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in complement activation, lectin pathway IMP
IMP: 通过突变表型推断
18424734 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
18424734 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

mannan-binding lectin serine protease 1

MASP-1

complement factor MASP-3

complement-activating component of Ra-reactive factor

mannose-binding lectin-associated serine protease 1

mannose-binding protein-associated serine protease

ra-reactive factor serine protease p100

raRF

serine proteas

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Masp1 NCBI NCBI:5648
Macaca fascicularis Masp1 NCBI NCBI:101866962
Rattus norvegicus Masp1 NCBI NCBI:64023