2. Gene
  3. Masp1 - MBL associated serine protease 1 Gene

Masp1 - MBL associated serine protease 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Masp3; Masp1/3

基因 ID: 64023 | 基因类型: protein coding

关于 Masp1

功能概要

Enables several functions, including calcium-dependent protein binding activity; protein homodimerization activity; and serine-type endopeptidase activity. Predicted to be involved in complement activation, lectin pathway and negative regulation of complement activation. Located in extracellular space. Human ortholog(s) of this gene implicated in 3MC syndrome 1. Orthologous to human MASP1 (MBL associated serine protease 1). [provided by Alliance of Genome Resources, Apr 2022]

Masp1 基因产物(1)

mRNA Protein Name
NM_022257.2 NP_071593.2 mannan-binding lectin serine protease 1 precursor
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables calcium ion binding IDA
IDA: 通过直接分析推断
10913141 RGD
enables calcium-dependent protein binding IPI
IPI: 通过物理相互作用推断
10913141 RGD
enables protein homodimerization activity IPI
IPI: 通过物理相互作用推断
10913141 RGD
enables serine-type endopeptidase activity IDA
IDA: 通过直接分析推断
15060079 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
12847554 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

mannan-binding lectin serine protease 1

MASP-1

complement factor MASP-3

complement-activating component of Ra-reactive factor

mannan-binding lectin serine peptidase 1

mannan-binding lectin serine protease 2-like

mannose-binding lectin-associated serine protease 1

mannose-binding protein a

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS08159 MASP1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17421 Masp1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23876 Masp1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Masp1 NCBI NCBI:5648
Macaca fascicularis Masp1 NCBI NCBI:101866962
Mus musculus Masp1 NCBI NCBI:17174
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