2. Gene
  3. Mki67 - antigen identified by monoclonal antibody Ki 67 Gene

Mki67 - antigen identified by monoclonal antibody Ki 67 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Ki67; Ki-67; D630048A14Rik

基因 ID: 17345 | 基因类型: protein coding

关于 Mki67

功能概要

Predicted to enable protein C-terminus binding activity. Involved in regulation of chromatin organization. Acts upstream of or within cholangiocyte proliferation; hepatocyte proliferation; and meiotic cell cycle. Located in chromosome; cytoplasm; and nucleolus. Is expressed in several structures, including alimentary system; brain; genitourinary system; sensory organ; and skin. Human ortholog(s) of this gene implicated in Crohn's disease; breast cancer; human immunodeficiency virus infectious disease; and pancreatic Cancer. Orthologous to human MKI67 (marker of proliferation Ki-67). [provided by Alliance of Genome Resources, Apr 2022]

Mki67 基因产物(1)

mRNA Protein Name
NM_001081117.2 NP_001074586.2 proliferation marker protein Ki-67
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cell population proliferation IDA
IDA: 通过直接分析推断
12972605 MGI
NOT involved in cell population proliferation IMP
IMP: 通过突变表型推断
26949251 MGI
acts upstream of or within cholangiocyte proliferation IDA
IDA: 通过直接分析推断
25446530 MGI
acts upstream of or within epithelial cell proliferation IDA
IDA: 通过直接分析推断
19303854 MGI
acts upstream of or within hepatocyte proliferation IDA
IDA: 通过直接分析推断
25446530 MGI
acts upstream of or within meiotic cell cycle IDA
IDA: 通过直接分析推断
12355204 MGI
involved in regulation of chromatin organization IMP
IMP: 通过突变表型推断
26949251 MGI
acts upstream of or within stem cell proliferation IDA
IDA: 通过直接分析推断
19303854 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in chromosome, centromeric region IDA
IDA: 通过直接分析推断
12355204 MGI
located in condensed chromosome IDA
IDA: 通过直接分析推断
12355204 MGI
located in cytoplasm IDA
IDA: 通过直接分析推断
11731231 MGI
located in nucleolus IDA
IDA: 通过直接分析推断
12355204 MGI
located in nucleus IDA
IDA: 通过直接分析推断
15237214 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

proliferation marker protein Ki-67

antigen KI-67 homolog

antigen Ki67 homolog

antigen identified by monoclonal antibody Ki-67 homolog

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-175266 MI1013 / 否
HY-RS08470 MKI67 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21649 Mki67 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28167 Mki67 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mki67 NCBI NCBI:4288
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