1. Gene
  2. Gadd45b - growth arrest and DNA-damage-inducible 45 beta Gene

Gadd45b - growth arrest and DNA-damage-inducible 45 beta Gene

种属: Mus musculus

同用名: Myd118

基因 ID: 17873 | 基因类型: protein coding

关于 Gadd45b

功能概要

Acts upstream of or within negative regulation of protein kinase activity; positive regulation of MAPK cascade; and regulation of cell cycle. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including arterial system; forelimb bud; future brain; sensory organ; and somite. Orthologous to human GADD45B (growth arrest and DNA damage inducible beta). [provided by Alliance of Genome Resources, Apr 2022]

Gadd45b 基因产物(1)

mRNA Protein Name
NM_008655.1 NP_032681.1 growth arrest and DNA damage-inducible protein GADD45 beta
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
12124778 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within negative regulation of protein kinase activity IDA
IDA: 通过直接分析推断
12124778 MGI
acts upstream of or within positive regulation of MAPK cascade IDA
IDA: 通过直接分析推断
12213961 MGI
acts upstream of or within regulation of cell cycle IDA
IDA: 通过直接分析推断
12124778 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

growth arrest and DNA damage-inducible protein GADD45 beta

myeloid differentiation primary response gene 118

myeloid differentiation primary response protein MyD118

negative growth regulatory protein MyD118

Gadd45b 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属间
Gadd45b P22339 GADD45GIP1 Homo sapiens Q8TAE8 12716909
种属间
Gadd45b P22339 GADD45GIP1 Homo sapiens Q8TAE8 12716909
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Gadd45b NCBI NCBI:4616