2. Gene
  3. Myo1c - myosin IC Gene

Myo1c - myosin IC Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: NMI; MMIb; myr2; MYO1E; mm1beta

基因 ID: 17913 | 基因类型: protein coding

关于 Myo1c

功能概要

This gene encodes a member of the unconventional Myosin protein family, which are actin-based molecular motors. The protein is found in the cytoplasm, and one isoform with a unique N-terminus is also found in the nucleus. The protein functions in intracellular vesicle transport to the plasma membrane. The nuclear isoform associates with RNA polymerase I and II and functions in transcription initiation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Myo1c 基因产物(4)

mRNA Protein Name
NM_001080774.2 NP_001074243.1 unconventional myosin-Ic isoform b
NM_001080775.2 NP_001074244.1 unconventional myosin-Ic isoform a
NM_001370611.2 NP_001357540.1 unconventional myosin-Ic isoform c
NM_008659.4 NP_032685.1 unconventional myosin-Ic isoform b
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables microfilament motor activity EXP
EXP: 通过实验结果推断
19046570 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
15976448 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cellular response to type II interferon IDA
IDA: 通过直接分析推断
19144319 MGI
acts upstream of or within positive regulation of cellular response to insulin stimulus IDA
IDA: 通过直接分析推断
12490950 MGI
acts upstream of or within positive regulation of cellular response to insulin stimulus IMP
IMP: 通过突变表型推断
12490950 MGI
acts upstream of or within positive regulation of protein targeting to membrane IDA
IDA: 通过直接分析推断
12490950 MGI
acts upstream of or within positive regulation of protein targeting to membrane IMP
IMP: 通过突变表型推断
12490950 MGI
acts upstream of or within vesicle transport along actin filament IDA
IDA: 通过直接分析推断
12490950 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in brush border IDA
IDA: 通过直接分析推断
15758024 MGI
located in cytoplasmic vesicle membrane IDA
IDA: 通过直接分析推断
12490950 MGI
located in phagocytic vesicle IDA
IDA: 通过直接分析推断
19144319 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
12490950 MGI
located in stereocilium IDA
IDA: 通过直接分析推断
17050716 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

unconventional myosin-Ic

MMI-beta

myosin I beta

myosin-Ibeta

myosin-Ic

nuclear myosin I beta

Myo1c 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Myo1c Q9WTI7 Plekhb1 Mus musculus Q9QYE9-1
Anti Tag CoIP
15976448
种属内
Myo1c Q9WTI7 Plekhb1 Mus musculus Q9QYE9-1
Pull Down
15976448
种属内
Myo1c Q9WTI7 Plekhb1 Mus musculus Q9QYE9-2
Y2H
15976448
种属内
Myo1c Q9WTI7 Plekhb1 Mus musculus Q9QYE9-2
Pull Down
15976448
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS08939 MYO1C Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS08941 MYO1E Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21659 Myo1c Mouse Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Myo1c NCBI NCBI:4641
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