1. Gene
  2. Ncf4 - neutrophil cytosolic factor 4 Gene

Ncf4 - neutrophil cytosolic factor 4 Gene

种属: Mus musculus

同用名: p40phox

基因 ID: 17972 | 基因类型: protein coding

关于 Ncf4

功能概要

Predicted to enable phosphatidylinositol-3-phosphate binding activity and superoxide-generating NADPH Oxidase activator activity. Predicted to be involved in superoxide anion generation. Located in cytoplasm. Is expressed in liver; lower urinary tract; stomach; and testis. Human ortholog(s) of this gene implicated in autosomal recessive chronic granulomatous disease cytochrome b-positive type III and rheumatoid arthritis. Orthologous to human NCF4 (neutrophil cytosolic factor 4). [provided by Alliance of Genome Resources, Apr 2022]

Ncf4 基因产物(4)

mRNA Protein Name
NM_001411421.1 NP_001398350.1 neutrophil cytosol factor 4 isoform 2
NM_001411422.1 NP_001398351.1 neutrophil cytosol factor 4 isoform 1
NM_001411423.1 NP_001398352.1 neutrophil cytosol factor 4 isoform 1
NM_008677.3 NP_032703.2 neutrophil cytosol factor 4 isoform 1
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
9490028 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
15850784 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

neutrophil cytosol factor 4

NCF-4

neutrophil NADPH oxidase factor 4

p40-phox

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ncf4 NCBI NCBI:4689