2. Gene
  3. Ndrg1 - N-myc downstream regulated gene 1 Gene

Ndrg1 - N-myc downstream regulated gene 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: RTP; DRG1; NMSL; Ndr1; Ndrl; TDD5; CAP43; CMT4D; HMSNL; PROXY1

基因 ID: 17988 | 基因类型: protein coding

关于 Ndrg1

功能概要

Predicted to enable Cadherin binding activity; small GTPase binding activity; and tubulin binding activity. Involved in negative regulation of cell population proliferation and peripheral nervous system myelin maintenance. Acts upstream of or within mast cell activation. Located in cytoplasm. Is expressed in several structures, including alimentary system; brain; early conceptus; genitourinary system; and sensory organ. Used to study Charcot-Marie-Tooth disease type 4D. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 4D. Orthologous to human NDRG1 (N-myc downstream regulated 1). [provided by Alliance of Genome Resources, Apr 2022]

Ndrg1 基因产物(1)

mRNA Protein Name
NM_008681.2 NP_032707.2 protein NDRG1
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within mast cell activation IDA
IDA: 通过直接分析推断
12804568 MGI
involved in negative regulation of cell population proliferation IMP
IMP: 通过突变表型推断
23555679 MGI
involved in peripheral nervous system myelin maintenance IMP
IMP: 通过突变表型推断
15082788 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
15082788 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

protein NDRG1

N-myc downstream regulated 1

N-myc downstream-regulated gene 1 protein

protein Ndr1

相关产品

Clinical Phase
生物活性分子 (4)
目录号 产品名 作用方式
纯度 Phase
HY-145723 MAX-40279 Inhibitor 97.04% Phase 2
HY-145723C MAX-40279 hemiadipate Inhibitor 99.26% Phase 2
HY-145723A MAX-40279 hydrochloride Inhibitor / Phase 2
HY-145723B MAX-40279 hemifumarate Inhibitor 99.56% Phase 2
Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-125878 PROTAC SGK3 degrader-1 Inhibitor 99.89% 否
HY-RS17382 Ndrg1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS09114 NDRG1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23837 Ndrg1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ndrg1 NCBI NCBI:10397
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