2. Gene
  3. Nfe2 - nuclear factor, erythroid derived 2 Gene

Nfe2 - nuclear factor, erythroid derived 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: p45; NF-E2; p45NFE2; p45nf-e2; NF-E2/P45

基因 ID: 18022 | 基因类型: protein coding

关于 Nfe2

功能概要

Predicted to enable several functions, including WW domain binding activity; identical protein binding activity; and protein N-terminus binding activity. Predicted to contribute to cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including labyrinthine layer blood vessel development; negative regulation of bone mineralization; and negative regulation of syncytium formation by plasma membrane fusion. Located in nucleus. Is expressed in several structures, including dorsal aorta; eye; genitourinary system; limb; and yolk sac. Orthologous to human NFE2 (nuclear factor, erythroid 2). [provided by Alliance of Genome Resources, Apr 2022]

Nfe2 基因产物(7)

mRNA Protein Name
NM_001302338.2 NP_001289267.1 transcription factor NF-E2 45 kDa subunit
NM_001302339.2 NP_001289268.1 transcription factor NF-E2 45 kDa subunit
NM_001302340.2 NP_001289269.1 transcription factor NF-E2 45 kDa subunit
NM_001302341.2 NP_001289270.1 transcription factor NF-E2 45 kDa subunit
NM_001302343.2 NP_001289272.1 transcription factor NF-E2 45 kDa subunit
NM_001400376.1 NP_001387305.1 transcription factor NF-E2 45 kDa subunit
NM_008685.4 NP_032711.2 transcription factor NF-E2 45 kDa subunit
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
19822740 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of bone mineralization IMP
IMP: 通过突变表型推断
15005853 MGI
acts upstream of cell population proliferation IDA
IDA: 通过直接分析推断
11113182 MGI
acts upstream of or within cell-cell signaling IMP
IMP: 通过突变表型推断
15005853 MGI
acts upstream of or within gene expression IDA
IDA: 通过直接分析推断
28411267 MGI
acts upstream of or within gene expression IMP
IMP: 通过突变表型推断
28411267 MGI
acts upstream of or within labyrinthine layer blood vessel development IMP
IMP: 通过突变表型推断
21558372 MGI
acts upstream of or within negative regulation of bone mineralization IMP
IMP: 通过突变表型推断
15005853 MGI
acts upstream of or within negative regulation of cell population proliferation IDA
IDA: 通过直接分析推断
11113182 MGI
acts upstream of or within negative regulation of syncytium formation by plasma membrane fusion IGI
IGI: 通过遗传相互作用推断
21558372 MGI
acts upstream of or within negative regulation of syncytium formation by plasma membrane fusion IMP
IMP: 通过突变表型推断
21558372 MGI
acts upstream of or within positive regulation of peptidyl-lysine acetylation IMP
IMP: 通过突变表型推断
21558372 MGI
acts upstream of or within regulation of gene expression IDA
IDA: 通过直接分析推断
11113182 MGI
acts upstream of syncytium formation by plasma membrane fusion IGI
IGI: 通过遗传相互作用推断
21558372 MGI
acts upstream of syncytium formation by plasma membrane fusion IMP
IMP: 通过突变表型推断
21558372 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
7995373 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

transcription factor NF-E2 45 kDa subunit

leucine zipper protein NF-E2

nuclear factor, erythroid derived 2, 45 kDa

nuclear factor, erythroid-derived 2 45 kDa subunit

Nfe2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Nfe2 Q07279 Ciita Mus musculus P79621
Pull Down
20211142
种属内
Nfe2 Q07279 Rps27a Mus musculus P62991
Anti Bait CoIP
19966288
种属内
Nfe2 Q07279 Ehmt2 Mus musculus Q9Z148-1
Anti Bait CoIP
19822740
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (17)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-12213 CDDO-EA Activator 99.78% 否
HY-145390 Nrf2 activator-1 Activator 98.66% 否
HY-RS09245 NFE2L2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-145390A (R,R)-Nrf2 activator-1 Activator 96.88% 否
HY-RS09246 Nfe2l2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-N6802 Tigloylgomisin H Inducer / 否
HY-RS09243 NFE2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS09244 NFE2L1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS09247 Nfe2l2 Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS09248 NFE2L3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18144 Nfe2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19795 Nfe2l3 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20770 Mafk Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21165 Nfe2l1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24619 Nfe2 Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26291 Nfe2l3 Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27681 Nfe2l1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Nfe2 NCBI NCBI:4778
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