2. Gene
  3. Pax5 - paired box 5 Gene

Pax5 - paired box 5 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: KLP; BSAP; EBB-1; Pax-5

基因 ID: 18507 | 基因类型: protein coding

关于 Pax5

功能概要

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including adult behavior; animal organ development; and negative regulation of nitrogen compound metabolic process. Located in nucleus. Is expressed in several structures, including central nervous system; future brain; liver; thymus; and urinary system. Human ortholog(s) of this gene implicated in acute lymphoblastic leukemia. Orthologous to human PAX5 (paired box 5). [provided by Alliance of Genome Resources, Apr 2022]

Pax5 基因产物(1)

mRNA Protein Name
NM_008782.3 NP_032808.1 paired box protein Pax-5
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA binding IDA
IDA: 通过直接分析推断
14594818 MGI
enables DNA binding IMP
IMP: 通过突变表型推断
16618805 MGI
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
12244173 MGI
enables DNA-binding transcription factor activity IDA
IDA: 通过直接分析推断
14594818 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
12244173 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
11799127 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within adult behavior IMP
IMP: 通过突变表型推断
23349049 MGI
acts upstream of or within cerebral cortex development IMP
IMP: 通过突变表型推断
23349049 MGI
acts upstream of or within embryonic cranial skeleton morphogenesis IMP
IMP: 通过突变表型推断
23349049 MGI
acts upstream of or within lateral ventricle development IMP
IMP: 通过突变表型推断
23349049 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
15258579 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
16618805 MGI
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
12244173 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IGI
IGI: 通过遗传相互作用推断
15094381 MGI
acts upstream of or within regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
14594818 MGI
acts upstream of or within skeletal muscle cell differentiation IMP
IMP: 通过突变表型推断
22147266 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
14594818 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

paired box protein Pax-5

B-cell-specific transcription factor

paired box gene 5

Pax5 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Pax5 Q02650 Paxip1 Mus musculus Q6NZQ4
Anti Bait CoIP
21552207
种属间
Pax5 Q02650 DAXX Homo sapiens Q9UER7
Pull Down
11799127
种属间
Pax5 Q02650 DAXX Homo sapiens Q9UER7
CoIP
11799127
种属间
Pax5 Q02650 DAXX Homo sapiens Q9UER7
Y2H
11799127
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10092 PAX5 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20318 Pax5 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26826 Pax5 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pax5 NCBI NCBI:5079
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