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  3. Pdk2 - pyruvate dehydrogenase kinase, isoenzyme 2 Gene

Pdk2 - pyruvate dehydrogenase kinase, isoenzyme 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

基因 ID: 18604 | 基因类型: protein coding

关于 Pdk2

功能概要

Enables pyruvate dehydrogenase (acetyl-transferring) kinase activity. Involved in several processes, including Insulin Receptor signaling pathway; regulation of acetyl-CoA biosynthetic process from pyruvate; and regulation of gluconeogenesis. Acts upstream of or within regulation of calcium-mediated signaling. Located in mitochondrion. Part of mitochondrial pyruvate dehydrogenase complex. Is expressed in heart. Orthologous to human PDK2 (pyruvate dehydrogenase kinase 2). [provided by Alliance of Genome Resources, Apr 2022]

Pdk2 基因产物(2)

mRNA Protein Name
NM_001361915.1 NP_001348844.1 pyruvate dehydrogenase kinase, isoenzyme 2 isoform 2
NM_133667.2 NP_598428.2 pyruvate dehydrogenase kinase, isoenzyme 2 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
15102471 MGI
enables pyruvate dehydrogenase (acetyl-transferring) kinase activity IMP
IMP: 通过突变表型推断
22360721 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to nutrient IMP
IMP: 通过突变表型推断
22360721 MGI
involved in glucose homeostasis IMP
IMP: 通过突变表型推断
22360721 MGI
involved in insulin receptor signaling pathway IMP
IMP: 通过突变表型推断
22360721 MGI
involved in regulation of acetyl-CoA biosynthetic process from pyruvate IMP
IMP: 通过突变表型推断
22360721 MGI
acts upstream of or within regulation of calcium-mediated signaling IMP
IMP: 通过突变表型推断
23357539 MGI
involved in regulation of cellular ketone metabolic process IMP
IMP: 通过突变表型推断
22360721 MGI
involved in regulation of gluconeogenesis IMP
IMP: 通过突变表型推断
22360721 MGI
involved in regulation of glucose metabolic process IMP
IMP: 通过突变表型推断
22360721 MGI
involved in regulation of pH IMP
IMP: 通过突变表型推断
22360721 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrion IDA
IDA: 通过直接分析推断
21190881 MGI
part of pyruvate dehydrogenase complex IDA
IDA: 通过直接分析推断
21190881 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

pyruvate dehydrogenase kinase, isoenzyme 2

PDH kinase 2

[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial

[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, mitochondrial

pyruvate dehydrogenase 2

pyruvate dehydrogenase kinase, isozyme 2

相关产品

Pre-clinical Phase
生物活性分子 (7)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-121744 PS10 Inhibitor 98.51% 否
HY-12492 VER-246608 Inhibitor 99.10% 否
HY-19564 JX06 99.78% 否
HY-18676B ILK-IN-2 99.41% 否
HY-RS10276 PDK2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS16924 Pdk2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23367 Pdk2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pdk2 NCBI NCBI:5164
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