1. Gene
  2. Phf2 - PHD finger protein 2 Gene

Phf2 - PHD finger protein 2 Gene

种属: Mus musculus

同用名: GRC5

基因 ID: 18676 | 基因类型: protein coding

关于 Phf2

功能概要

Enables histone H4-methyl-lysine-20 demethylase activity. Involved in epigenetic maintenance of chromatin in transcription-competent conformation; histone H3-K9 demethylation; and histone H4-K20 demethylation. Predicted to be located in kinetochore; nucleolus; and nucleoplasm. Is expressed in several structures, including alimentary system; eye; genitourinary system; nervous system; and respiratory system. Orthologous to human PHF2 (PHD finger protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Phf2 基因产物(1)

mRNA Protein Name
NM_011078.3 NP_035208.2 lysine-specific demethylase PHF2
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables histone H4K20 demethylase activity IMP
IMP: 通过突变表型推断
22921934 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
22921934 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in transcription initiation-coupled chromatin remodeling IMP
IMP: 通过突变表型推断
22921934 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

lysine-specific demethylase PHF2

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Phf2 NCBI NCBI:5253