2. Gene
  3. Pik3r2 - phosphoinositide-3-kinase regulatory subunit 2 Gene

Pik3r2 - phosphoinositide-3-kinase regulatory subunit 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: p85beta

基因 ID: 18709 | 基因类型: protein coding

关于 Pik3r2

功能概要

Enables phosphatidylinositol 3-kinase regulatory subunit binding activity and protein heterodimerization activity. Involved in several processes, including cellular glucose homeostasis; Insulin Receptor signaling pathway; and positive regulation of protein import into nucleus. Acts upstream of or within positive regulation of cell adhesion; regulation of actin filament organization; and regulation of protein localization to plasma membrane. Located in focal adhesion and nucleus. Is expressed in several structures, including early embryo; genitourinary system; liver; musculature; and spleen. Human ortholog(s) of this gene implicated in pancreatic ductal adenocarcinoma. Orthologous to human PIK3R2 (phosphoinositide-3-kinase regulatory subunit 2). [provided by Alliance of Genome Resources, Apr 2022]

Pik3r2 基因产物(1)

mRNA Protein Name
NM_008841.3 NP_032867.2 phosphatidylinositol 3-kinase regulatory subunit beta
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables phosphatidylinositol 3-kinase regulatory subunit binding IPI
IPI: 通过物理相互作用推断
20348926 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
12052866 MGI
enables protein heterodimerization activity IPI
IPI: 通过物理相互作用推断
20348926 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to insulin stimulus IDA
IDA: 通过直接分析推断
20348926 MGI
involved in insulin receptor signaling pathway IMP
IMP: 通过突变表型推断
20348926 MGI
involved in intracellular glucose homeostasis IDA
IDA: 通过直接分析推断
20348926 MGI
acts upstream of or within positive regulation of cell adhesion IDA
IDA: 通过直接分析推断
25217619 MGI
involved in positive regulation of protein import into nucleus IMP
IMP: 通过突变表型推断
20348926 MGI
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
20348926 MGI
acts upstream of or within regulation of actin filament polymerization IMP
IMP: 通过突变表型推断
25217619 MGI
acts upstream of or within regulation of protein localization to plasma membrane IDA
IDA: 通过直接分析推断
25217619 MGI
acts upstream of or within regulation of stress fiber assembly IMP
IMP: 通过突变表型推断
25217619 MGI
involved in response to endoplasmic reticulum stress IDA
IDA: 通过直接分析推断
20348926 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in focal adhesion IDA
IDA: 通过直接分析推断
25217619 MGI
located in nucleus IDA
IDA: 通过直接分析推断
20348926 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

phosphatidylinositol 3-kinase regulatory subunit beta

PI3-kinase regulatory subunit beta

PI3-kinase subunit p85-beta

PI3K regulatory subunit beta

phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta

phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta)

ptdIns-3-kinase regul

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-174976 FHND5032 Inhibitor / 否
HY-RS10537 PIK3R2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21907 Pik3r2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28424 Pik3r2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pik3r2 NCBI NCBI:5296
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z