1. Gene
  2. Pld3 - phospholipase D family, member 3 Gene

Pld3 - phospholipase D family, member 3 Gene

种属: Mus musculus

同用名: Sam-9

基因 ID: 18807 | 基因类型: protein coding

关于 Pld3

功能概要

Enables single-stranded DNA 5'-3' exodeoxyribonuclease activity. Involved in regulation of cytokine production involved in inflammatory response. Located in late endosome membrane and lysosomal membrane. Is expressed in several structures, including alimentary system; cardiovascular system; genitourinary system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in spinocerebellar ataxia 46. Orthologous to human PLD3 (Phospholipase D family member 3). [provided by Alliance of Genome Resources, Apr 2022]

Pld3 基因产物(2)

mRNA Protein Name
NM_001317355.1 NP_001304284.1 5'-3' exonuclease PLD3
NM_011116.2 NP_035246.1 5'-3' exonuclease PLD3
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
NOT enables phospholipase D activity IDA
IDA: 通过直接分析推断
9813063 MGI
enables single-stranded DNA 5'-3' DNA exonuclease activity IDA
IDA: 通过直接分析推断
30111894 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in regulation of cytokine production involved in inflammatory response IMP
IMP: 通过突变表型推断
22102906 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in late endosome membrane IDA
IDA: 通过直接分析推断
28128235 MGI
located in lysosomal membrane IDA
IDA: 通过直接分析推断
28128235 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

5'-3' exonuclease PLD3

PLD 3

choline phosphatase 3

phosphatidylcholine-hydrolyzing phospholipase D3

phospholipase D3

schwannoma-associated protein 9

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pld3 NCBI NCBI:23646