2. Gene
  3. Nos1ap - nitric oxide synthase 1 adaptor protein Gene

Nos1ap - nitric oxide synthase 1 adaptor protein Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Capon

基因 ID: 192363 | 基因类型: protein coding

关于 Nos1ap

功能概要

Enables PDZ domain binding activity; nitric-oxide synthase binding activity; and protease binding activity. Involved in several processes, including neuron projection regeneration; positive regulation of peptidyl-cysteine S-nitrosylation; and regulation of calcium ion transmembrane transport. Located in cytosol and nucleus. Is active in glutamatergic synapse; postsynapse; and presynapse. Colocalizes with nuclear membrane. Used to study mental depression. Biomarker of congestive heart failure and sciatic neuropathy. Human ortholog(s) of this gene implicated in nephrotic syndrome type 22. Orthologous to human NOS1AP (nitric oxide synthase 1 adaptor protein). [provided by Alliance of Genome Resources, Apr 2022]

Nos1ap 基因产物(1)

mRNA Protein Name
NM_138922.3 NP_620277.2 carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables PDZ domain binding IDA
IDA: 通过直接分析推断
9459447 RGD
enables mitogen-activated protein kinase kinase binding IPI
IPI: 通过物理相互作用推断
23658158 RGD
enables nitric-oxide synthase binding IDA
IDA: 通过直接分析推断
9459447 RGD
enables nitric-oxide synthase binding IPI
IPI: 通过物理相互作用推断
11086993 RGD
enables protease binding IPI
IPI: 通过物理相互作用推断
19553464 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
11086993 RGD
enables signaling adaptor activity IDA
IDA: 通过直接分析推断
9459447 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in neuron projection regeneration IEP
IEP: 通过表达模式推断
10762708 RGD
involved in positive regulation of peptidyl-cysteine S-nitrosylation IMP
IMP: 通过突变表型推断
24665357 RGD
involved in regulation of calcium ion transmembrane transport via high voltage-gated calcium channel IDA
IDA: 通过直接分析推断
24665357 RGD
involved in regulation of high voltage-gated calcium channel activity IDA
IDA: 通过直接分析推断
24665357 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytosol IDA
IDA: 通过直接分析推断
24665357 RGD
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
20357130 RGD
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
20357130 RGD
located in nuclear membrane IDA
IDA: 通过直接分析推断
24665357 RGD
located in nucleus IDA
IDA: 通过直接分析推断
24665357 RGD
is active in postsynapse IDA
IDA: 通过直接分析推断
20357130 RGD
is active in postsynapse IMP
IMP: 通过突变表型推断
20357130 RGD
is active in presynapse IDA
IDA: 通过直接分析推断
20357130 RGD
is active in presynapse IMP
IMP: 通过突变表型推断
20357130 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein

C-terminal PDZ domain ligand of neuronal nitric oxide synthase

C-terminal PDZ ligand of neuronal nitric oxide synthase protein

nitric oxide synthase 1 (neuronal) adaptor protein

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-124996 (Rac)-ZLc-002 Inhibitor 98.96% 否
HY-RS09436 NOS1AP Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19265 Nos1ap Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25754 Nos1ap Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Nos1ap NCBI NCBI:9722
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