1. Gene
  2. Ptprf - protein tyrosine phosphatase, receptor type, F Gene

Ptprf - protein tyrosine phosphatase, receptor type, F Gene

种属: Mus musculus

同用名: LAR; LARS; RPTP-LAR

基因 ID: 19268 | 基因类型: protein coding

关于 Ptprf

功能概要

Enables chondroitin sulfate proteoglycan binding activity. Acts upstream of or within neuron projection regeneration and regulation of axon regeneration. Located in neuron projection and neuronal cell body. Is expressed in several structures, including adrenal gland; alimentary system epithelium; central nervous system; genitourinary system; and nasal cavity epithelium. Human ortholog(s) of this gene implicated in hyperinsulinism. Orthologous to human PTPRF (protein tyrosine Phosphatase receptor type F). [provided by Alliance of Genome Resources, Apr 2022]

Ptprf 基因产物(2)

mRNA Protein Name
NM_011213.2 NP_035343.2 receptor-type tyrosine-protein phosphatase F precursor
NM_011213.2 NP_035343.2 receptor-type tyrosine-protein phosphatase F precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables chondroitin sulfate proteoglycan binding IPI
IPI: 通过物理相互作用推断
21976490 MGI
enables protein-containing complex binding IDA
IDA: 通过直接分析推断
23791195 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within neuron projection regeneration IMP
IMP: 通过突变表型推断
11438588 MGI
acts upstream of or within regulation of axon regeneration IMP
IMP: 通过突变表型推断
21976490 MGI
acts upstream of or within regulation of neuron projection development IMP
IMP: 通过突变表型推断
21976490 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in neuron projection IDA
IDA: 通过直接分析推断
11438588 MGI
located in neuronal cell body IDA
IDA: 通过直接分析推断
21976490 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

receptor-type tyrosine-protein phosphatase F

leukocyte antigen-related (LAR) PTP receptor

leukocyte common antigen related

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ptprf NCBI NCBI:5792