2. Gene
  3. Ptprj - protein tyrosine phosphatase, receptor type, J Gene

Ptprj - protein tyrosine phosphatase, receptor type, J Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: BET; Byp; Scc1; CD148; DEP-1; Ptpb2; RPTPJ; Scc-1; R-PTP-J; PTPbeta2; R-PTP-eta

基因 ID: 19271 | 基因类型: protein coding

关于 Ptprj

功能概要

Enables protein tyrosine Phosphatase activity. Involved in several processes, including regulation of cell migration; regulation of protein phosphorylation; and regulation of signal transduction. Acts upstream of or within heart development; oligodendrocyte differentiation; and vasculogenesis. Located in immunological synapse and ruffle membrane. Is expressed in midbrain; renal calyx; renal pelvis; and superior colliculus. Human ortholog(s) of this gene implicated in colorectal Cancer. Orthologous to human PTPRJ (protein tyrosine Phosphatase receptor type J). [provided by Alliance of Genome Resources, Apr 2022]

Ptprj 基因产物(2)

mRNA Protein Name
NM_001135657.1 NP_001129129.1 receptor-type tyrosine-protein phosphatase eta isoform 2
NM_008982.6 NP_033008.4 receptor-type tyrosine-protein phosphatase eta isoform 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein tyrosine phosphatase activity IMP
IMP: 通过突变表型推断
12771128 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in B cell differentiation IMP
IMP: 通过突变表型推断
18249142 MGI
involved in blood coagulation IMP
IMP: 通过突变表型推断
19246339 MGI
involved in glucose homeostasis IMP
IMP: 通过突变表型推断
26063811 MGI
acts upstream of or within heart development IMP
IMP: 通过突变表型推断
12588999 MGI
involved in negative regulation of MAP kinase activity IDA
IDA: 通过直接分析推断
12833140 MGI
involved in negative regulation of T cell receptor signaling pathway IDA
IDA: 通过直接分析推断
12913111 MGI
involved in negative regulation of cell migration IDA
IDA: 通过直接分析推断
12833140 MGI
involved in negative regulation of cell population proliferation IMP
IMP: 通过突变表型推断
12771128 MGI
involved in negative regulation of insulin receptor signaling pathway IMP
IMP: 通过突变表型推断
26063811 MGI
involved in negative regulation of platelet-derived growth factor receptor signaling pathway IDA
IDA: 通过直接分析推断
12833140 MGI
involved in negative regulation of signaling receptor activity IMP
IMP: 通过突变表型推断
12771128 MGI
acts upstream of or within oligodendrocyte differentiation IMP
IMP: 通过突变表型推断
19139271 MGI
involved in peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity IMP
IMP: 通过突变表型推断
26063811 MGI
involved in positive regulation of Fc receptor mediated stimulatory signaling pathway IGI
IGI: 通过遗传相互作用推断
18249142 MGI
involved in positive regulation of MAPK cascade IGI
IGI: 通过遗传相互作用推断
18249142 MGI
involved in positive regulation of calcium-mediated signaling IGI
IGI: 通过遗传相互作用推断
18249142 MGI
involved in positive regulation of cell-matrix adhesion IDA
IDA: 通过直接分析推断
12833140 MGI
involved in positive regulation of macrophage chemotaxis IDA
IDA: 通过直接分析推断
19268662 MGI
involved in positive regulation of peptidyl-tyrosine phosphorylation IGI
IGI: 通过遗传相互作用推断
18249142 MGI
involved in positive regulation of phagocytosis IGI
IGI: 通过遗传相互作用推断
18249142 MGI
involved in positive regulation of platelet activation IMP
IMP: 通过突变表型推断
19246339 MGI
involved in positive regulation of tumor necrosis factor production IGI
IGI: 通过遗传相互作用推断
18249142 MGI
acts upstream of or within vasculogenesis IMP
IMP: 通过突变表型推断
12588999 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in immunological synapse IDA
IDA: 通过直接分析推断
12913111 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
19268662 MGI
located in ruffle membrane IDA
IDA: 通过直接分析推断
19268662 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

receptor-type tyrosine-protein phosphatase eta

HPTP beta-like tyrosine phosphatase

colon tumor susceptibility 1

protein-tyrosine phosphatase eta

susceptibility to colon cancer 1

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS11441 PTPRJ Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18679 Ptprj Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25165 Ptprj Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ptprj NCBI NCBI:5795
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