2. Gene
  3. EFNA3 - ephrin A3 Gene

EFNA3 - ephrin A3 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：肾上腺素 A3

种属: Homo sapiens

同用名: EFL2; EPLG3; LERK3; Ehk1-L

基因 ID: 1944 | 基因类型: protein coding

关于 EFNA3

Cytogenetic location: 1q21.3 Genomic coordinates (GRCh38): 1:155,078,837-155,087,538 (from NCBI)

This gene has 3 transcripts (splice variants), 180 orthologues and 7 paralogues. Biased expression in skin (RPKM 20.5), esophagus (RPKM 8.1) and 3 other tissues.

功能概要

该基因编码肝配蛋白 (EPH) 家族的一个成员。肝配蛋白和 EPH 相关受体包含受体蛋白-酪氨酸激酶的最大亚家族，并且与介导发育事件有关，尤其是在神经系统和红细胞生成中。基于它们的结构和序列关系，肝配蛋白分为肝配蛋白-A (EFNA) 类和肝配蛋白 B (EFNB) 类，前者通过糖基磷脂酰肌醇键固定在膜上，后者是跨膜蛋白。该基因编码 EFNA 类肝配蛋白。[RefSeq 提供，2008 年 7 月]

This gene encodes a member of the ephrin (EPH) family. The Ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, Ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNA class ephrin. [provided by RefSeq, Jul 2008]

EFNA3 基因产物(1)

mRNA Protein Name
NM_004952.5 NP_004943.1 ephrin-A3 precursor

EFNA3 蛋白结构

Ephrin

Ephrin: Ephrin (29 - 170)

  • 0
  • 100
  • 200
  • 238 a.a.
蛋白主名 其他名称

ephrin-A3

EFL-2

重组 EFNA3 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70375 Ephrin-A3/EFNA3 Protein, Human (HEK293, His) P52797 (Q23-S211) ≥95%
HY-P73006 Ephrin-A3/EFNA3 Protein, Human (HEK293) P52797 (Q23-S213) ≥95%
HY-P73007 Ephrin-A3/EFNA3 Protein, Human (HEK293, Fc) P52797 (Q23-S213) ≥95%
HY-P73008 Ephrin-A3/EFNA3 Protein, Human (HEK293, His-Fc) P52797 (M1-S213) ≥95%

关联疾病

疾病名称 别名
Breast Cancer

Breast Carcinoma

Male Breast Cancer

Breast Cancer, Familial

Malignant Neoplasm Of Breast

Breast Cancer, Susceptibility To

Breast Cancer, Early-Onset

Malignant Tumor Of Breast

Carcinoma Of Male Breast

Breast Cancer, Invasive Ductal

Breast Cancer, Protection Against

Breast Cancer, Somatic

Breast Cancer, Male

Breast Cancer, Lobular, Somatic

Breast Tumor

Mammary Cancer

Mammary Tumor

Malignant Neoplasm Of Male Breast

Mammary Carcinoma

Male Breast Carcinoma

Familial Cancer Of Breast

Invasive Ductal Breast Carcinoma

Breast Cancer Susceptibility

Breast Cancer, Male, Susceptibility To

Breast Cancer, Early-Onset, Susceptibility To

Malignant Tumor Of The Breast

Mammary Neoplasm

Primary Breast Cancer

Neoplasm Of Male Breast

Carcinoma Of Breast

Breast Cancer In Men

Familial Breast Cancer

Cancer Of Breast

BC

Breast Cancer Familial

Breast Cancer Familial Male

Breast Cancer, Familial Male

Breast Male Carcinoma

Breast Neoplasms

Breast Neoplasms, Male

Mammary Tumors

Mammary Carcinomas

Cancer, Breast

Cancer, Breast, Susceptibility

Invasive Breast Ductal Carcinoma

Breast Neoplasm

Susceptibility To Breast Cancer

Mammary Neoplasms

Animal Mammary Neoplasms

Primary Malignant Neoplasm Of Breast

Infiltrating Ductal Carcinoma Of Breast

Infiltrating Duct Carcinoma Of Unspecified Site

Infiltrating Ductular Carcinoma Of Unspecified Site

Invasive Breast Carcinoma Of No Special Type

Microinvasive Carcinoma Of Breast

Carcinoma With Apocrine Differentiation
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04194 EFNA3 Human Pre-designed siRNA Set A / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus EFNA3 RGD RGD:620390
Mus musculus EFNA3 MGD MGI:106644
Others EFNA3 NCBI
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