2. Gene
  3. Robo1 - roundabout guidance receptor 1 Gene

Robo1 - roundabout guidance receptor 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: DUTT1; Gm310

基因 ID: 19876 | 基因类型: protein coding

关于 Robo1

功能概要

Predicted to enable LRR domain binding activity; axon guidance receptor activity; and identical protein binding activity. Involved in several processes, including circulatory system development; neuron development; and regulation of gene expression. Acts upstream of or within animal organ development; axon guidance; and negative regulation of cell population proliferation. Located in axolemma. Is expressed in several structures, including central nervous system; foot; genitourinary system; jaw; and sensory organ. Used to study cystic kidney disease and lung Cancer. Orthologous to human ROBO1 (roundabout guidance receptor 1). [provided by Alliance of Genome Resources, Apr 2022]

Robo1 基因产物(1)

mRNA Protein Name
NM_019413.2 NP_062286.2 roundabout homolog 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
19684588 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in aorta development IGI
IGI: 通过遗传相互作用推断
25691540 MGI
involved in aortic valve morphogenesis IGI
IGI: 通过遗传相互作用推断
25691540 MGI
acts upstream of or within axon guidance IMP
IMP: 通过突变表型推断
15084255 MGI
involved in axon midline choice point recognition IGI
IGI: 通过遗传相互作用推断
18986510 MGI
acts upstream of or within coronary vasculature development IMP
IMP: 通过突变表型推断
25807483 MGI
involved in endocardial cushion formation IGI
IGI: 通过遗传相互作用推断
25691540 MGI
acts upstream of or within heart development IMP
IMP: 通过突变表型推断
25807483 MGI
involved in heart induction IDA
IDA: 通过直接分析推断
25691540 MGI
acts upstream of or within kidney development IMP
IMP: 通过突变表型推断
27002738 MGI
acts upstream of or within mammary duct terminal end bud growth IMP
IMP: 通过突变表型推断
16439476 MGI
acts upstream of or within negative regulation of cell population proliferation IMP
IMP: 通过突变表型推断
18829537 MGI
involved in negative regulation of gene expression IDA
IDA: 通过直接分析推断
25691540 MGI
involved in olfactory bulb interneuron development IGI
IGI: 通过遗传相互作用推断
17360927 MGI
involved in outflow tract septum morphogenesis IGI
IGI: 通过遗传相互作用推断
25691540 MGI
involved in positive regulation of Notch signaling pathway IDA
IDA: 通过直接分析推断
25691540 MGI
involved in positive regulation of gene expression IDA
IDA: 通过直接分析推断
25691540 MGI
involved in pulmonary valve morphogenesis IGI
IGI: 通过遗传相互作用推断
25691540 MGI
acts upstream of or within ventricular septum development IMP
IMP: 通过突变表型推断
25807483 MGI
involved in ventricular septum morphogenesis IGI
IGI: 通过遗传相互作用推断
25691540 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axolemma IDA
IDA: 通过直接分析推断
15084255 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

roundabout homolog 1

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS12110 ROBO1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-175200 DEL-S1 / 否
HY-RS20096 Robo1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26599 Robo1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Robo1 NCBI NCBI:6091
Rattus norvegicus Robo1 NCBI NCBI:58946
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