2. Gene
  3. Ncor1 - nuclear receptor co-repressor 1 Gene

Ncor1 - nuclear receptor co-repressor 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: N-CoR; RIP13; Rxrip13; mKIAA1047; 5730405M06Rik; A230020K14Rik

基因 ID: 20185 | 基因类型: protein coding

关于 Ncor1

功能概要

Enables several functions, including histone deacetylase regulator activity; nuclear receptor binding activity; and transcription corepressor activity. Involved in locomotor rhythm. Acts upstream of or within several processes, including hemopoiesis; regulation of gene expression; and regulation of signal transduction. Located in cytoplasm and nucleus. Part of transcription repressor complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Orthologous to human NCOR1 (nuclear receptor corepressor 1). [provided by Alliance of Genome Resources, Apr 2022]

Ncor1 基因产物(3)

mRNA Protein Name
NM_001252313.1 NP_001239242.1 nuclear receptor corepressor 1 isoform 1
NM_011308.3 NP_035438.3 nuclear receptor corepressor 1 isoform 2
NM_177229.3 NP_796203.1 nuclear receptor corepressor 1 isoform 3
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA binding IDA
IDA: 通过直接分析推断
14980219 MGI
enables chromatin binding IDA
IDA: 通过直接分析推断
17392792 MGI
enables histone deacetylase regulator activity IDA
IDA: 通过直接分析推断
19037247 MGI
enables histone deacetylase regulator activity IMP
IMP: 通过突变表型推断
15695367 MGI
enables nuclear retinoic acid receptor binding IDA
IDA: 通过直接分析推断
8961273 MGI
enables nuclear retinoid X receptor binding IDA
IDA: 通过直接分析推断
7760852 MGI
enables nuclear thyroid hormone receptor binding IDA
IDA: 通过直接分析推断
8961273 MGI
enables nuclear thyroid hormone receptor binding IPI
IPI: 通过物理相互作用推断
19052228 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
9139821 MGI
enables protein domain specific binding IPI
IPI: 通过物理相互作用推断
15175761 MGI
enables sequence-specific DNA binding IDA
IDA: 通过直接分析推断
17928865 MGI
enables transcription cis-regulatory region binding IDA
IDA: 通过直接分析推断
16127449 MGI
enables transcription corepressor activity IGI
IGI: 通过遗传相互作用推断
7566114 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation IMP
IMP: 通过突变表型推断
11030619 MGI
acts upstream of or within T cell differentiation in thymus IMP
IMP: 通过突变表型推断
11030619 MGI
acts upstream of or within cellular response to Thyroglobulin triiodothyronine IGI
IGI: 通过遗传相互作用推断
24550004 MGI
acts upstream of or within cholesterol homeostasis IMP
IMP: 通过突变表型推断
19052228 MGI
acts upstream of or within circadian regulation of gene expression IGI
IGI: 通过遗传相互作用推断
19037247 MGI
acts upstream of or within definitive erythrocyte differentiation IMP
IMP: 通过突变表型推断
11030619 MGI
involved in epidermis development IGI
IGI: 通过遗传相互作用推断
32467224 MGI
involved in establishment of skin barrier IGI
IGI: 通过遗传相互作用推断
32467224 MGI
involved in gene expression IGI
IGI: 通过遗传相互作用推断
32467224 MGI
involved in in utero embryonic development IGI
IGI: 通过遗传相互作用推断
32467224 MGI
involved in locomotor rhythm IMP
IMP: 通过突变表型推断
19037247 MGI
acts upstream of or within negative regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
15695367 MGI
acts upstream of or within negative regulation of DNA-templated transcription IMP
IMP: 通过突变表型推断
15681609 MGI
involved in negative regulation of DNA-templated transcription IMP
IMP: 通过突变表型推断
24794873 MGI
acts upstream of or within negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IMP
IMP: 通过突变表型推断
17606624 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IGI
IGI: 通过遗传相互作用推断
7566114 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
11328825 MGI
involved in protein stabilization IGI
IGI: 通过遗传相互作用推断
32467224 MGI
acts upstream of or within regulation of multicellular organism growth IGI
IGI: 通过遗传相互作用推断
19037247 MGI
acts upstream of or within regulation of thyroid hormone receptor signaling pathway IGI
IGI: 通过遗传相互作用推断
24550004 MGI
acts upstream of or within regulation of transcription by RNA polymerase II IGI
IGI: 通过遗传相互作用推断
19052228 MGI
acts upstream of or within thalamus development IMP
IMP: 通过突变表型推断
11030619 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
17606624 MGI
located in nucleus IDA
IDA: 通过直接分析推断
11092755 MGI
part of transcription regulator complex IPI
IPI: 通过物理相互作用推断
17182846 MGI
part of transcription repressor complex IPI
IPI: 通过物理相互作用推断
17182846 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

nuclear receptor corepressor 1

N-CoR1

retinoid X receptor-interacting protein 13

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-121900 LT175 Agonist 99.79% 否
HY-RS09096 NCOR1 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS20452 Ncor1 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS26961 Ncor1 Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ncor1 NCBI NCBI:9611
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