2. Gene
  3. Sod1 - superoxide dismutase 1, soluble Gene

Sod1 - superoxide dismutase 1, soluble Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Ipo1; SODC; Ipo-1; Sod-1; CuZnSOD; Cu/Zn-SOD; B430204E11Rik

基因 ID: 20655 | 基因类型: protein coding

关于 Sod1

功能概要

Enables superoxide dismutase activity. Involved in axonal transport; negative regulation of inflammatory response; and positive regulation of phagocytosis. Acts upstream of or within several processes, including hydrogen peroxide biosynthetic process; muscle cell cellular homeostasis; and neurogenesis. Located in extracellular space. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Used to study amyotrophic lateral sclerosis type 1; dry eye syndrome; and low tension glaucoma. Human ortholog(s) of this gene implicated in several diseases, including Down syndrome; artery disease (multiple); eye disease (multiple); glucose metabolism disease (multiple); and neurodegenerative disease (multiple). Orthologous to human SOD1 (superoxide dismutase 1). [provided by Alliance of Genome Resources, Apr 2022]

Sod1 基因产物(1)

mRNA Protein Name
NM_011434.2 NP_035564.1 superoxide dismutase [Cu-Zn]
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
2960971 MGI
enables superoxide dismutase activity IDA
IDA: 通过直接分析推断
291939 MGI
enables superoxide dismutase activity IMP
IMP: 通过突变表型推断
8673102 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within action potential initiation IMP
IMP: 通过突变表型推断
30952836 MGI
involved in anterograde axonal transport IMP
IMP: 通过突变表型推断
20510358 MGI
acts upstream of apoptotic process IMP
IMP: 通过突变表型推断
16036348 MGI
acts upstream of or within auditory receptor cell stereocilium organization IMP
IMP: 通过突变表型推断
10464373 MGI
acts upstream of or within determination of adult lifespan IMP
IMP: 通过突变表型推断
16377630 MGI
acts upstream of ectopic germ cell programmed cell death IMP
IMP: 通过突变表型推断
16036348 MGI
acts upstream of or within embryo implantation IMP
IMP: 通过突变表型推断
9516486 MGI
acts upstream of or within gene expression IMP
IMP: 通过突变表型推断
30952836 MGI
acts upstream of or within glutathione metabolic process IMP
IMP: 通过突变表型推断
16377630 MGI
acts upstream of or within heart contraction IMP
IMP: 通过突变表型推断
10679476 MGI
acts upstream of or within hydrogen peroxide biosynthetic process IMP
IMP: 通过突变表型推断
14679182 MGI
acts upstream of or within intracellular iron ion homeostasis IMP
IMP: 通过突变表型推断
16377630 MGI
acts upstream of or within locomotory behavior IMP
IMP: 通过突变表型推断
10433959 MGI
acts upstream of or within muscle cell cellular homeostasis IMP
IMP: 通过突变表型推断
16716900 MGI
acts upstream of or within myeloid cell homeostasis IGI
IGI: 通过遗传相互作用推断
11493445 MGI
acts upstream of or within myeloid cell homeostasis IMP
IMP: 通过突变表型推断
11493445 MGI
acts upstream of or within negative regulation of apoptotic process IDA
IDA: 通过直接分析推断
12223545 MGI
acts upstream of or within negative regulation of apoptotic process IMP
IMP: 通过突变表型推断
16036348 MGI
acts upstream of or within negative regulation of developmental process IMP
IMP: 通过突变表型推断
16036348 MGI
involved in negative regulation of inflammatory response IGI
IGI: 通过遗传相互作用推断
25381879 MGI
acts upstream of or within negative regulation of neuron apoptotic process IMP
IMP: 通过突变表型推断
10464373 MGI
acts upstream of or within negative regulation of reproductive process IMP
IMP: 通过突变表型推断
16036348 MGI
acts upstream of or within neurofilament cytoskeleton organization IGI
IGI: 通过遗传相互作用推断
11343650 MGI
acts upstream of or within neurofilament cytoskeleton organization IMP
IMP: 通过突变表型推断
11343650 MGI
acts upstream of or within neuronal action potential IMP
IMP: 通过突变表型推断
30952836 MGI
acts upstream of or within ovarian follicle development IMP
IMP: 通过突变表型推断
9724058 MGI
acts upstream of or within peripheral nervous system myelin maintenance IMP
IMP: 通过突变表型推断
10433959 MGI
acts upstream of or within positive regulation of MAPK cascade IDA
IDA: 通过直接分析推断
12223545 MGI
involved in positive regulation of phagocytosis IGI
IGI: 通过遗传相互作用推断
25381879 MGI
acts upstream of or within regulation of blood pressure IMP
IMP: 通过突变表型推断
12433839 MGI
acts upstream of or within regulation of multicellular organism growth IMP
IMP: 通过突变表型推断
16377630 MGI
acts upstream of or within relaxation of vascular associated smooth muscle IMP
IMP: 通过突变表型推断
12433839 MGI
acts upstream of or within removal of superoxide radicals IGI
IGI: 通过遗传相互作用推断
11493445 MGI
acts upstream of or within removal of superoxide radicals IMP
IMP: 通过突变表型推断
8673102 MGI
acts upstream of or within response to axon injury IMP
IMP: 通过突变表型推断
8673102 MGI
acts upstream of or within response to ethanol IMP
IMP: 通过突变表型推断
17448893 MGI
acts upstream of or within response to heat IMP
IMP: 通过突变表型推断
16942767 MGI
acts upstream of or within response to hydrogen peroxide IMP
IMP: 通过突变表型推断
15642323 MGI
acts upstream of or within response to oxidative stress IDA
IDA: 通过直接分析推断
12223545 MGI
acts upstream of or within response to oxidative stress IMP
IMP: 通过突变表型推断
16716900 MGI
acts upstream of or within response to reactive oxygen species IMP
IMP: 通过突变表型推断
17059387 MGI
acts upstream of or within response to superoxide IMP
IMP: 通过突变表型推断
9516486 MGI
acts upstream of or within response to xenobiotic stimulus IMP
IMP: 通过突变表型推断
16831125 MGI
acts upstream of or within retina homeostasis IMP
IMP: 通过突变表型推断
16844785 MGI
involved in retrograde axonal transport IMP
IMP: 通过突变表型推断
20510358 MGI
acts upstream of or within sensory perception of sound IMP
IMP: 通过突变表型推断
10436316 MGI
acts upstream of or within spermatogenesis IMP
IMP: 通过突变表型推断
16036348 MGI
acts upstream of or within superoxide anion generation IDA
IDA: 通过直接分析推断
15317809 MGI
acts upstream of or within superoxide metabolic process IMP
IMP: 通过突变表型推断
11404260 MGI
acts upstream of or within transmission of nerve impulse IMP
IMP: 通过突变表型推断
10433959 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
15634772 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

superoxide dismutase [Cu-Zn]

Cu(2+)-Zn2+ superoxide dismutase

相关产品

Approval
生物活性分子 (1)
目录号 产品名 作用方式
纯度 是否罕见病
HY-132580 Tofersen 96.53% 否
Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-16074 ATN-224 98.0% Phase 2
Pre-clinical Phase
生物活性分子 (19)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-115445 LCS-1 99.81% 否
HY-W115718 Cuprizone 99.61% 否
HY-132580A Tofersen sodium 97.19% 否
HY-133968 24-Methylenecholesterol 99.48% 否
HY-153019 NUCC-0000323 Inhibitor 99.86% 否
HY-123982 SOD1-Derlin-1 inhibitor-2 Inhibitor 99.86% 否
HY-138131 SOD1-Derlin-1 inhibitor-1 Inhibitor 99.93% 否
HY-148901 CMB-087229 Inhibitor 98.05% 否
HY-173025 Nurr1 agonist 12 Agonist / 否
HY-RS13559 SOD1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-133968S1 24-Methylenecholesterol-13C / 否
HY-145294 ROCK2-IN-5 Inhibitor / 否
HY-163772 Fraxinellone analog 1 Activator / 否
HY-172152 MP-010 / 否
HY-176827 SOD1-IN-1 Inhibitor / 否
HY-E70377 Cu/Zn Superoxide dismutase / 否
HY-P10627 SOD1 (147-153) human / 否
HY-RS16926 Sod1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23369 Sod1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Sod1 NCBI NCBI:6647
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