1. Gene
  2. Rnf43 - ring finger protein 43 Gene

Rnf43 - ring finger protein 43 Gene

种属: Mus musculus

同用名: 4732452J19Rik

基因 ID: 207742 | 基因类型: protein coding

关于 Rnf43

功能概要

Predicted to enable Frizzled binding activity and ubiquitin protein Ligase activity. Involved in negative regulation of Wnt signaling pathway and stem cell proliferation. Predicted to be located in endoplasmic reticulum; nucleus; and plasma membrane. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. Is expressed in alimentary system; genitourinary system; and lung. Orthologous to human RNF43 (Ring Finger Protein 43). [provided by Alliance of Genome Resources, Apr 2022]

Rnf43 基因产物(2)

mRNA Protein Name
NM_001363437.1 NP_001350366.1 E3 ubiquitin-protein ligase RNF43 isoform 2
NM_172448.4 NP_766036.2 E3 ubiquitin-protein ligase RNF43 isoform 1 precursor
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
31073040 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of Wnt signaling pathway IMP
IMP: 通过突变表型推断
22895187 MGI
involved in stem cell proliferation IMP
IMP: 通过突变表型推断
22895187 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

E3 ubiquitin-protein ligase RNF43

RING-type E3 ubiquitin transferase RNF43

重组 Rnf43 蛋白

目录号 产品名 蛋白编号 纯度
HY-P78030 RNF43 Protein, Mouse (HEK293, Fc) Q5NCP0-1 (G24-Y197) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Rnf43 NCBI NCBI:54894
Canis familiaris Rnf43 NCBI NCBI:491114