1. Gene
  2. Lzts1 - leucine zipper, putative tumor suppressor 1 Gene

Lzts1 - leucine zipper, putative tumor suppressor 1 Gene

种属: Mus musculus

同用名: F37; FEZ1; PSD-Zip70

基因 ID: 211134 | 基因类型: protein coding

关于 Lzts1

功能概要

Predicted to enable microtubule binding activity. Predicted to be involved in negative regulation of macroautophagy; regulation of dendrite morphogenesis; and regulation of synaptic plasticity. Predicted to be located in several cellular components, including apical plasma membrane; dendritic shaft; and postsynaptic density. Predicted to be active in dendritic spine. Is expressed in several structures, including brain and metanephros. Human ortholog(s) of this gene implicated in esophageal Cancer and squamous cell carcinoma. Orthologous to human LZTS1 (leucine zipper tumor suppressor 1). [provided by Alliance of Genome Resources, Apr 2022]

Lzts1 基因产物(2)

mRNA Protein Name
NM_001370971.1 NP_001357900.1 leucine zipper putative tumor suppressor 1
NM_199364.3 NP_955396.2 leucine zipper putative tumor suppressor 1
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in regulation of postsynapse assembly IDA
IDA: 通过直接分析推断
26490870 MGI
involved in regulation of postsynapse assembly IMP
IMP: 通过突变表型推断
26490870 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
26490870 MGI
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
26490870 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

leucine zipper putative tumor suppressor 1

F37 esophageal cancer-related leucine zipper motif 1

F37/Esophageal cancer-related gene-coding leucine-zipper motif

leucine-zipper protein FEZ1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Lzts1 NCBI NCBI:11178