2. Gene
  3. Satb2 - special AT-rich sequence binding protein 2 Gene

Satb2 - special AT-rich sequence binding protein 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: BAP002; mKIAA1034

基因 ID: 212712 | 基因类型: protein coding

关于 Satb2

功能概要

Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and chromatin binding activity. Acts upstream of or within several processes, including generation of neurons; regulation of transcription by RNA polymerase II; and skeletal system development. Located in nucleus. Part of histone deacetylase complex and transcription regulator complex. Is expressed in several structures, including 1st branchial arch; cerebral cortex; facial prominence; genitourinary system; and limb. Used to study isolated cleft palate. Human ortholog(s) of this gene implicated in SATB2-associated syndrome. Orthologous to human SATB2 (SATB homeobox 2). [provided by Alliance of Genome Resources, Apr 2022]

Satb2 基因产物(3)

mRNA Protein Name
NM_001358580.1 NP_001345509.1 DNA-binding protein SATB2
NM_001358581.1 NP_001345510.1 DNA-binding protein SATB2
NM_139146.2 NP_631885.1 DNA-binding protein SATB2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
15733084 MGI
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
16751105 MGI
enables chromatin binding IDA
IDA: 通过直接分析推断
16751105 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
16751105 MGI
enables sequence-specific DNA binding IGI
IGI: 通过遗传相互作用推断
16751105 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cartilage development IMP
IMP: 通过突变表型推断
16751105 MGI
acts upstream of or within chromatin remodeling IDA
IDA: 通过直接分析推断
18255031 MGI
acts upstream of or within embryonic pattern specification IMP
IMP: 通过突变表型推断
16751105 MGI
acts upstream of or within embryonic skeletal system morphogenesis IMP
IMP: 通过突变表型推断
16751105 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
16751105 MGI
acts upstream of or within neuron migration IMP
IMP: 通过突变表型推断
18255031 MGI
acts upstream of or within osteoblast development IGI
IGI: 通过遗传相互作用推断
16751105 MGI
acts upstream of or within osteoblast development IMP
IMP: 通过突变表型推断
16751105 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
16751105 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IGI
IGI: 通过遗传相互作用推断
16751105 MGI
acts upstream of or within regulation of gene expression IMP
IMP: 通过突变表型推断
18255031 MGI
acts upstream of or within roof of mouth development IMP
IMP: 通过突变表型推断
16751105 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of histone deacetylase complex IDA
IDA: 通过直接分析推断
18255031 MGI
located in nucleus IDA
IDA: 通过直接分析推断
15733084 MGI
part of transcription regulator complex IDA
IDA: 通过直接分析推断
16751105 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

DNA-binding protein SATB2

KIAA1034-like DNA binding protein

two cut domains-containing homeodomain protein

Satb2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Satb2 Q8VI24 Ski Mus musculus Q60698
Anti Bait CoIP
22334647
种属内
Satb2 Q8VI24 Hdac1 Mus musculus O09106
Anti Bait CoIP
22334647
种属内
Satb2 Q8VI24 Hdac1 Mus musculus O09106
Anti Bait CoIP
30726206
种属内
Satb2 Q8VI24 Cux1 Mus musculus P53564
Anti Bait CoIP
30726206
种属内
Satb2 Q8VI24 Mta2 Mus musculus Q9R190
Anti Bait CoIP
22334647
种属内
Satb2 Q8VI24 Mta2 Mus musculus Q9R190
Anti Bait CoIP
30726206
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS12458 SATB2 Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Satb2 NCBI NCBI:23314
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