1. Gene
  2. Tacr2 - tachykinin receptor 2 Gene

Tacr2 - tachykinin receptor 2 Gene

中文名称:速激肽受体 2

种属: Mus musculus

同用名: Skr; Nk2r; Tac2r

基因 ID: 21337 | 基因类型: protein coding

关于 Tacr2

Chromosome 10: 62,088,217-62,101,769 forward strand.GRCm39:CM001003.3

This gene has 1 transcript (splice variant), 200 orthologues, 55 paralogues and is associated with 2 phenotypes. Biased expression in adrenal adult (RPKM 85.1), colon adult (RPKM 9.6) and 1 other tissue.

功能概要

预测该基因编码的蛋白编码的蛋白可启动物质 K 受体活性。参与调节子宫平滑肌收缩。预测位于膜内;精子鞭毛;和精子头。预计在质膜和精子中段有活性。在肾上腺中表达。该基因的人类直系同源物与哮喘有关。与人 TACR2(速激肽受体 2)同源。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable substance K receptor activity. Involved in regulation of uterine smooth muscle contraction. Predicted to be located in membrane; sperm flagellum; and sperm head. Predicted to be active in plasma membrane and sperm midpiece. Is expressed in adrenal gland. Human ortholog(s) of this gene implicated in asthma. Orthologous to human TACR2 (tachykinin receptor 2). [provided by Alliance of Genome Resources, Apr 2022]

Tacr2 基因产物(1)

mRNA Protein Name
NM_009314.4 NP_033340.3 substance-K receptor
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in regulation of uterine smooth muscle contraction IDA
IDA: 通过直接分析推断
15647454 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

Tacr2 蛋白结构

7tmA_SKR_NK2R

7tmA_SKR_NK2R: cd16004 (33 - 317)

7tmA_SKR_NK2R

7tmA_SKR_NK2R: cd16004 (34 - 60)

7tmA_SKR_NK2R

7tmA_SKR_NK2R: cd16004 (67 - 93)

7tmA_SKR_NK2R

7tmA_SKR_NK2R: cd16004 (105 - 135)

7tmA_SKR_NK2R

7tmA_SKR_NK2R: cd16004 (146 - 167)

7tmA_SKR_NK2R

7tmA_SKR_NK2R: cd16004 (193 - 222)

7tmA_SKR_NK2R

7tmA_SKR_NK2R: cd16004 (242 - 272)

7tmA_SKR_NK2R

7tmA_SKR_NK2R: cd16004 (285 - 310)

  • 0
  • 100
  • 200
  • 300
  • 384 a.a.
蛋白主名 其他名称

substance-K receptor

7 transmembrane receptor

NK-2 receptor

NK-2R

neurokinin A receptor

tachykinin NK-2 receptor

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tacr2 NCBI NCBI:6865