1. Gene
  2. Tbxas1 - thromboxane A synthase 1, platelet Gene

Tbxas1 - thromboxane A synthase 1, platelet Gene

种属: Mus musculus

同用名: TS; TXS; CYP5; THAS; TXAS; CYP5A1

基因 ID: 21391 | 基因类型: protein coding

关于 Tbxas1

功能概要

Enables thromboxane-A synthase activity. Predicted to be involved in cellular chloride ion homeostasis; positive regulation of vasoconstriction; and prostaglandin biosynthetic process. Predicted to act upstream of or within fatty acid biosynthetic process and prostaglandin metabolic process. Predicted to be located in endoplasmic reticulum membrane. Is expressed in several structures, including bone marrow; brain; liver; lung; and metanephros. Human ortholog(s) of this gene implicated in Ghosal hematodiaphyseal syndrome; cerebral infarction; and platelet-type bleeding disorder 14. Orthologous to human TBXAS1 (thromboxane A synthase 1). [provided by Alliance of Genome Resources, Apr 2022]

Tbxas1 基因产物(4)

mRNA Protein Name
NM_001410475.1 NP_001397404.1 thromboxane-A synthase isoform 2
NM_001410476.1 NP_001397405.1 thromboxane-A synthase isoform 3
NM_001410477.1 NP_001397406.1 thromboxane-A synthase isoform 4
NM_011539.4 NP_035669.3 thromboxane-A synthase isoform 1
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables thromboxane-A synthase activity IMP
IMP: 通过突变表型推断
7688225 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

thromboxane-A synthase

TXA synthase

cytochrome P450 5A1

hydroperoxy icosatetraenoate dehydratase

thromboxane synthase

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tbxas1 NCBI NCBI:6916