2. Gene
  3. Tfam - transcription factor A, mitochondrial Gene

Tfam - transcription factor A, mitochondrial Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Hmgts; mtTFA; tsHMG

基因 ID: 21780 | 基因类型: protein coding

关于 Tfam

功能概要

Enables mitochondrial promoter sequence-specific DNA binding activity. Involved in mitochondrial transcription. Acts upstream of or within mitochondrial respiratory chain complex assembly. Located in mitochondrial nucleoid. Is expressed in several structures, including brain; branchial arch; early conceptus; genitourinary system; and hemolymphoid system. Used to study Kearns-Sayre syndrome and Parkinson's disease. Human ortholog(s) of this gene implicated in Alzheimer's disease; Huntington's disease; Parkinson's disease; amyotrophic lateral sclerosis; and mitochondrial DNA depletion syndrome 15. Orthologous to human TFAM (transcription factor A, mitochondrial). [provided by Alliance of Genome Resources, Apr 2022]

Tfam 基因产物(1)

mRNA Protein Name
NM_009360.4 NP_033386.1 transcription factor A, mitochondrial precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables mitochondrial promoter sequence-specific DNA binding IDA
IDA: 通过直接分析推断
2628167 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within mitochondrial respiratory chain complex assembly IMP
IMP: 通过突变表型推断
11259653 MGI
involved in mitochondrial transcription IDA
IDA: 通过直接分析推断
2628167 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrial nucleoid IDA
IDA: 通过直接分析推断
24703694 MGI
is active in mitochondrion IDA
IDA: 通过直接分析推断
2628167 MGI
located in mitochondrion IDA
IDA: 通过直接分析推断
8673128 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

transcription factor A, mitochondrial

TS-HMG

testis-specific HMG-box protein m-tsHMG

testis-specific high mobility group protein

相关产品

Pre-clinical Phase
生物活性分子 (6)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-N3225 Myricanol 98.0% 否
HY-RS14407 TFAM Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-172199 THX6 / 否
HY-175739 TFAM activator 1 / 否
HY-RS17056 Tfam Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23500 Tfam Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tfam NCBI NCBI:7019
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